Scientific Studies DATABASE PAGE1


Prezint mai jos, cateva MII de STUDII STIINTIFICE(in vivo si in vitro, atat pe animale cat si pe oameni, cazuri clinice) referitor la doar cateva din cele prezentate pe acest site si in carte despre TRATAREA EFICIENTA A CANCERULUI, BAZATA PE  si DEMONSTRATA DE STIINTA.

Aceasta din 2 motive:

1. Am dorit sa va ofer o doza in plus de incredere in dvs, incredere care trebuie sa vina in urma unor studii stiintifice credibile, NU in urma unor „marturii” ale unor oameni pe care nu ii cunoasteti, cu atat mai putin in urma unor  pareri personale, indiferent ale cui sunt.

2. Cele mai multe siteuri de tratare alternativa a cancerului(si ma refer incolusiv la mari siteuri internationale) efectiv uita sa faca acest lucru si lumea pune la indoiala cele promovate si este „pacat” ( sa spun cel putin ) intr-ucat TRATAMENTELE ALTERNATIVE sunt SINGURELE CARE OFERA SANSE(si spun acest lucru bazat pe studii, NU pe pareri personale).

Acest site si carte prezinta si CITEAZA STUDII si NU pareri NICI marturii ale unor persoane necunoscute.

CLICK AICI pentru  limba ROmana(traducerea „aproximativa” in utilizand google translate)

EN:Here you will find „some” scientific studies ,both „in vitro” and „in vivo”, both on animals and on humans and clinical trials regarding some of the  treatments promoted by this website – in fact, you will find a solid scientific database, demonstrated by multiple independent studies to give you confidence you need in alternative medicine(confidence that should be based on facts(i.e independent studies) not on testimonials or „opinions” that are always subjective).



  • STUDIES regarding cancer causes
  • STUDIES on MINERALS(ORGANIC) : organic Boron, organic Calcium,organic CESIUM, organic Chromium, organic Germanium, Organic  Iodine, organic Iron, organic Magnesium, organic Manganese, organic Molybdenum, organic Selenium, organic Silicium, organic Vanadium, organic Zinc,etc. Examples: CALCIUM, CESIUM,  GERMANIUM , POTASSIUM, RUBIDIUM, IODINE, SELENIUM,ZINC


  • Vitamins in alphabetical order:
  1. Vitamin A
  2. B Vitamins
    Vitamin B2 – Riboflavin, Vitamin B3(Niacin),
    Vitamin B5 ( pantotenic acid )(respiratory vitamins), Vitamin B6,B12, B17
  3. Vitamin C (very important vitamin, also respiratory vitamin)
  4. Vitamin D(very important vitamin)
  5. Vitamin E (respiratory vitamin)
  6. Vitamin F(including Omega 3)
  7. Vitamin K & Vitamin K antagonists


  • Algae(Seaweed : Spirulina, Chlorella, Kombu(Fucoidan), etc.):
  • Aloe Family( i.e. :Vera ,Arborescens)
  • BetaGlucans(i.e.: Medicinal Mushrooms)
  • Bee products( honey,polen, propolis, venom, royal jelly)


  • Carotenoids
  1. Alpha-Carotene
  2. β-Carotene
  3. β-Cyptoxanthin
  4. Astaxanthin
  5. Canthaxanthin
  6. Lutein/Zeaxanthin
  7. Lycopene
  • Coenzyme Q10


  • Flavonoids:

  1. Flavonoid Subclass Dietary Flavonoids
    Anthocyanidins Cyanidin, Delphinidin, Malvidin, Pelargonidin, Peonidin, Petunidin
    Flavanols Monomers (Catechins):Catechin, Epicatechin, Epigallocatechin Epicatechin gallate, Epigallocatechin gallateDimers and Polymers:Theaflavins, Thearubigins,Proanthocyanidins
    Flavanones Hesperetin, Naringenin, Eriodictyol
    Flavonols Quercetin, Kaempferol, Myricetin, Isorhamnetin
    Flavones Apigenin, Luteolin
    Isoflavones Daidzein, Genistein, Glycitein



  • Hydroxycinnamic Acids
    • Chicoric acid
    • Coumarin
    • Ferulic acid

  • Isoprenoides :Abscisic acid, Acorenone, Alloaromadendrene, Aromadendrene, Bergamotene, Bisabolene,Borneol, Bornyl acetate, Isoborneol, Cadinene, Camphene, Caranol, Carene, Carvacrol, Carvone,Pinocarvone, Caryophyllene, Cedrine, Cineole, Cinnamaldehyde, Cinnamate, Citral,Cinnamaldehyde, Cyclocitral, Citronella, Citronellyl acetate or butyrate or propionate, Copaene, Cresol, Cubebene, Cymene, Damascenone,Elemene, Estragol, Eugenol, Farnesene, Fencone, Geraniol, Germacrene, Hotrienol, Humulene, Ionol, Ionone, Isopinocamphone, Isopulegol, Linalool, Longifolene, Mentol, Neomenthol, Menthone, Isomenthone, Murolene, Myrcenol, Myrcene, Myrtenol, Neral, Nerol, Nerolidol, Nootkatone, Ocimene, Ocimenol, Perillaldehyde, Phellandrene, Pinene, Pinocamphone, Piperitol,Piperitone, Pristane, Pulegone, Sabinene, Sabinol, Santalol, Selinadiene, Selinene, Sinensal, Styrene, Terpinene, Terpineol, Terpinolene, Thymol, Tricyclene, Vanillin, Valencene,
  • Lecithins 
  • Lignans (Silymarin)
  • Monophenols 
  •              Hydroxytyrosol
  • Monoterpenes
    • Geraniol
    • Limonene
  • Organosulfides
    • Allicin
    • Glutathione
    • Indole-3-Carbinol & Di-Indole Methane
    • Isothiocyanates
    • Sulforaphane
  • Phenolic Acids
    • Capsaicin
    • Ellagic acid
    • Galic Acid
    • Rosmarinic acid
    • Tannic Acid
  • Phytosterols
    • Beta-Sitosterol
  • Saponins
  • Stilbenes: 1. Pterostilbene 2. RESVERATROL
  • Oxindole alkaloids
  • Styryl-lactones : Altholactone, Goniothalamin,etc
  • Tannins:
  • 1) the condensed tannins (Proanthocyanidin)
  • 2) the hydrolysable tannins (as hydrolysable Ellagitannins, such as Woodfordin C (macrocyclic ellagitannin dimmer), Oenotheietc.Anthocyanins: Peonidine-3-glucoside, Cyanidin-3-glucoside , etc.
  • Terpenes:  Alisol B acetate, Atractylon, Atractylenolides, Betulinic acid, Bisabolol, Boswellic acid, Carnosic acid,Ferutidin, Ferutinin, Myristicin, Oleanolic acid, Parthenolide, Pomolic acid, Tymoquinone, …etc…
  • Vanillys-phenols : Paradols, Gingerols, Yakuchinone B, Curcumin (diferuloyl methane), Capsaicin (homo-vanillic acid derivative : 8 methyl-N-Vanillyl-6-nonenamide),etc. Curcumin
  • Triterpenoids :
  • Ursolic acid

  • Other Phytochemicals
    • Damnacanthal
    • Digoxin
    • Phytic acid
  • Other things: Melatonin


  • Scientific studies on Anticarcinogenic natural substances
  • Hundreds of studies about NATURAL substances with DEMONSTRATED chemopreventive effect:
  • Hundreds of studies about NATURAL substances with DEMONSTRATED Chemotherapeutic effect:
  • APOPTOSIS & hundreds of studies about NATURAL substances with DEMONSTRATED APOPTOTIC effect
  • Hundreds of studies about NATURAL substances with DEMONSTRATED ANTIPROLIFERATIVE effect
  • Scientific studies on Anti-Angiogenic
  • Immune therapy & studies about NATURAL substances with DEMONSTRATED immune strengthening effect


  • a list of about 1600 scientific papers quoted in the book of Dr. Nacci (see my book for more details) in thename of the “Evidence Based Medicine”, which provides this medical method:



STUDIES regarding cancer causes:

O. Warburg won the Nobel Prize in Medicine in 1931 for his discovery of the oxygen-transferring enzyme of cell respiration and prime cause of cancer cells- inadequate/improper oxygenation replaced by glucose fermentation, and was voted a second Nobel Prize in 1944 for his discovery of the active groups of the hydrogryuen transferring enzymes.

Many universities, like Harvard, Oxford, Heidelberg has offered him honorary degrees. He is a Foreign member of the Royal Society if London, a Knight of the Order of Merit founded by Frederick the Great, and was awarded the Great Cross with Star and Shoulder ribbon of the Bundesrepublik.

His main interests are Chemistry and Physics of Life. In both fields no scientists has been more successful.

Excerpts from The Prime Cause and Prevention of Cancer:

Dr. Otto Warburg lecture delivered to Nobel Laureates on June 30, 1966 at Lindau, Lake Constance, Germany:

„There are prime and secondary causes of diseases. For example, the prime cause of the plague is the plague bacillus, but secondary causes of the plague are filth, rats, and the fleas that transfer the plague bacillus from rats to man.

By the prime cause of a disease, I mean one that is found in every case of the disease.

Cancer, above all other diseases, has countless secondary causes. Almost anything can cause cancer. But, even for cancer, there is only one prime cause. The prime cause of cancer is the replacement of the respiration of oxygen (oxidation of sugar) in normal body cells by fermentation of sugar.

All normal body cells meet their energy needs by respiration of oxygen, whereas cancer cells meet their energy needs in great part by fermentation. All normal body cells are thus obligate aerobes, whereas all cancer cells are partial anaerobes.

From the standpoint of the physics and chemistry of life this difference between normal and cancer cells is so great that one can scarcely picture a greater difference.

Oxygen gas, the donor of energy in plants and animals, is dethroned in the cancer cells and replaced by the energy yielding reaction of the lowest living forms, namely the fermentation of sugar. I

n every case, during the cancer development, the oxygen respiration always falls, fermentation appears, and the highly differentiated cells are transformed into fermenting anaerobes, which have lost all their body functions and retain only the now useless property of growth and replication.

Thus, when respiration disappears, life does not disappear, but the meaning of life disappears, and what remains are growing machines that destroy the body in which they grow. All carcinogens impair respiration directly or indirectly by deranging capillary circulation, a statement that is proven by the fact that no cancer cell exists without exhibiting impaired respiration. Of course, respiration cannot be repaired if it is impaired at the same time by a carcinogen.

To prevent cancer it is therefore proposed first to keep the speed of the blood stream so high that the venous blood still contains sufficient oxygen; second, to keep high the concentration of hemoglobin in the blood; third, to add always to the food, even of healthy people, the active groups of the respiratory enzymes; and to increase the doses of these groups, if a precancerous state has already developed. If at the same time exogenous carcinogens are excluded rigorously, then much of the endogenous cancer may be prevented today.

These proposals are in no way utopian. On the contrary, they may be realized by everybody, everywhere, at any hour. Unlike the prevention of many other diseases, the prevention of cancer requires no government help, and not much money. Many experts agree that one could prevent about 80% of all cancers in man, if one could keep away the known carcinogens from the normal body cells. But how can the remaining 20%, the so-called spontaneous cancers, be prevented? It is indisputable that all cancer could be prevented if the respiration of body cells were kept intact.”

Information Sources:

For his discovery of the nature and mode of action of the respiratory enzyme, the Nobel Prize was awarded to Otto Warburg in 1931. This discovery opened up new ways in the fields of cellular metabolism and cellular respiration. He showed, among other things, that cancerous cells can live and develop, even in the absence of oxygen.

Otto Warburg, won his first Nobel Prize in 1931 for his discovery of the oxygen transferring enzyme of cell respiration and his second Nobel Prize in 1944 for his discovery of the hydrogen transferring enzyme.

His discoveries are quoted…as follows:

„But, even for cancer, there is only one primary cause. Summarized in a few words, the cause of cancer is the replacement of the respiration of oxygen in normal body cells by a fermentation of sugar. Because no cancer cell exists, the respiration of which is intact, it cannot be disputed that cancer could be prevented if the respiration of the body cells would be kept intact.”

Dr. Otto Warburg received the Nobel prize in 1931 for the discovery that unlike all other cells in the human body, cancer cells do not breathe oxygen. Cancer cells are anaerobic, which means that they derive their energy without needing oxygen.

Otto Wartburg’s research revealed that when a cell does not receive 60% of its normal oxygen needs, it goes to a mechanism of fermentation and uncontrolled increase.

Many scientists have confirmed Dr. Otto Wartburg’s discovery, using various scientific methods and techniques(from  Gaston Naessens using the Dark-field microscope  to recent studies in 2012 ) :        

long-term lack of oxygen in cells is the key driver of cancer growth.

Read more recent studies that confirm :

Also read Cancer CAUSES (click here), for studies regarding indirect causes(i.e.:microbes, acidosis, free radicals, radiation, etc.)


Regarding cancer treatments:

Minerals (organic) :

organic Boron, organic Calcium,organic CESIUM, organic Chromium, organic Germanium, Organic  Iodine, organic Iron, organic Magnesium, organic Manganese, organic Molybdenum, organic Selenium, organic Silicium, organic Vanadium, organic Zinc,etc.


Calcium is an alkaline mineral that carries oxygen to healthy cells, among others.

Every cancer treatment requires alkalinity to slow down the spread of the cancer.

While Cesium (See below) and few other treatments contain alkaline minerals, every other cancer treatment needs calcium to provide the alkalinity.The reason this is a required addition is that calcium, combined with Vitamin D, contains the critical alkalinity.

Though I am not in favor of calcium supplements I suggest coral calcium .

Vitamin D is critical for the calcium to be absorbed(see below studies about Vitamin D ,CAlcium and cancer).

Vitamin D is BEST taken form exposure to natural sunlight( without any sunscreen or protection); the more sunshine , the better(avoi burning and exposure between 11am- 16 pm).

The vitamin D3 doses should NOT be elevated, but should always be the doses on the bottle.

If you taking a multi-vitamin, make sure you do not take too much Vitamin D or Vitamin D3.

These pills should be taken during meals. When taken with meals, apple juice or oranges should be consumed in order for the body to better absorb the calcium. Also, other fruits and vegetables should be consumed during the meal to insure the calcium is better absorbed.

The calcium product should be 100% coral calcium. There are some products that mix calcium from coral reefs with calcium from other sources. A cancer patient should not take unnecessary risks but should insure all of the calcium in the product is coral calcium.

No matter what else you do, I would also suggest the patient take at least two oranges a day (for the Vitamin D) and at least one banana a day (for the potassium).

This protocol is an optional treatment for anyone on one of the baking soda protocols.

The Robert Barefoot Coral Calcium Protocol For Treating Cancer

The following information was obtained mainly from the book: The Calcium Factor: The Scientific Secret of Health and Youth,by Robert R. Barefoot and Dr. Carl J. Reich, M.D. The information came from Chapters 14 and 17, though I have made some changes to his supplement dosages (I believe Robert Barefoot wrote this chapter) because the supplement doses he talks about are for a generic disease prevention program.

If you use this as a treatment, you might want to buy the book, though a lot of it was written for chemists. The book is sold from the same website that sells the coral calcium and vitamin D3.It has some really good testimonials for many diseases.

Quote from the The Calcium Factor book:

  • „The program will help to alkalize the body’s fluids, resulting in the toxins, which are adhered to the cell surface, detaching themselves and entering the blood. The body will recognize the toxins as foreign invaders and respond by attacking them possibly causing flu-like symptoms like headaches, stomach aches and diarrhea. This is called ‘de-toxing’ and it means that the body is ridding itself of cancer inducing compounds.”
    The Calcium Factor: The Scientific Secret of Health and Youth, Page 145

If you have any of these symptoms, it is a good thing because it means the treatment is working.

However, you may want to drop the dose down and „build-up” the dose over 4 or 5 days until you get to the recommended doses.

Studies on calcium and cancer

Studies on CAlcium and APOTOSIS:

Note: Apoptosis – programmed DEATH of CANCERous cells


I felt it only fair to mention the protocol of Robert R. Barefoot, the co-author of the excellent book: The Calcium Factor: The Scientific Secret of Health and Youth. The other author of this book is Dr. Carl J. Reich, M.D., who worked with Nobel Prize winner Dr. Otto Warburg before Warburg’s death.

Robert R. Barefoot is a big supporter of using calcium, namely coral calcium, in treating cancer. However, he also said the following in chapter 17 of his book:

„A terminal cancer patient, for example, may be cured over a 6 month period by consuming the proper nutrients, but may only have 3 weeks to live. This situation requires a more potent nutrient treatment such as cesium chloride, for example. Cesium chloride is a natural salt, and where it is found, cancer does not exist. This is because cesium is the most caustic mineral that exists, and when it enters the body, it seeks out all of the acidic cancer hotspots, dousing the fire of cancer, thereby terminating the cancer within days. Also, when dimethyl sulfoxide (DMSO) is rubbed near a painful cancer, the pain is removed and the DMSO causes the cesium to penetrate the cancer tumor much faster, thereby terminating the cancer much faster…”

The Calcium Factor: The Scientific Secret of Health and Youth, page 144

He also stated in his book: „The author has witnessed numerous people with terminal cancers who have employed the above program successfully.”

When it comes to the treatment of advanced cancer, stage IV cancers, rapidly growing cancers which have spread significantly, high mortality types of cancers or cancers that have spread to the bones Cesium Chloride protocol is one of the most proven existing cancer treatments. 

This treatment can be used by patients with new cancer diagnosis and by patients fed by feeding tubes or patients fed IntraVenously .

Technical details( :


Cesium is a rare, naturally occurring element of alkali metal, similar in chemical structure to lithium, sodium, and potassium. Cesium chloride is a salt form of this element.

Cesium chloride is most commonly associated with High pH Therapy and cancer, due to the work of Keith Brewer, Otto Warburg, and H.E.Sartori, among others. They found that cancer cells thrive in an anaerobic (low oxygen) environment with low pH values, and that raising the cell pH makes it hard for cancer cells to survive. Cesium, being one of the most alkaline elements, has a high pH value and is also readily taken up by cancer cells, thus raising their pH to a level at which they can no longer survive.

See also :


The cells of the body can only live within a certain pH range or they will die. When we eat or drink, we affect our body’s pH values. When we take in something acidic, or of low pH (low oxygen) values, the body either has to pull alkaline minerals from within itself to neutralize the acid, or store the acid somewhere in the tissue. If you drink an acidic soda at pH 2.5, it takes 32 glasses of water at pH 10 to neutralize the acid. And, as one’s pH drops, the cells’ oxygen levels also drop, and its ability to function properly and heal itself diminishes drastically. The pH number is an exponent number of 10; therefore, a small difference in pH translates to a big difference in the number of oxygen or OH- ions. A difference of 1 in a pH value means ten times the difference in the number of OH- ions, a difference of 2 means one hundred times the difference in the number of OH- ions. In other words, blood with a pH value of 7.45 contains 64.9% more oxygen than blood with a pH value of 7.30.


 „A normal cell undergoes an adverse change when it can no longer use the oxygen to convert glucose into energy by oxidation .. In the absence of oxygen the cell returns to a primitive nutritional program to sustain itself, converting glucose, by fermentation. lactic acid produced by fermentation lowers the cell pH (acid / alkaline balance) and destroys the ability of DNA and RNA to control cell division [..] cancer cells begin to multiply uncontrollably and  lactic acid simultaneously causes intense local pain and destroys cell enzymes .. Therefore, cancer appears as a rapidly growing mass of cells on the outside with a core cell death. ”

In the absence of oxygen, glucose is subjected to fermentation and creates lactic acid. This causes the pH to drop in the cell between 7.3 – 7.2 , down to 7 – 6.5, and in more advanced stages of cancer and metastasis sites pH can be lower than 6.0 and even 5.7.

The pH scale ranges from 0 to 14, with numbers below 7 representing an acidic (low oxygen) condition and above 7 representing an alkaline, or oxygenated, condition. When cesium is taken up by cancer cells, it raises the pH, or oxygen content, of the cell. The cells that die are absorbed and eliminated by the body. Cesium has been used to raise the pH of the body as an alternative or complementary cancer treatment or therapy for breast cancer, lung cancer, prostate cancer, colon cancer, pancreatic cancer, liver cancer, skin cancer, ovarian cancer, stomach cancer, cervical cancer, brain cancer, kidney cancer, testicular cancer, bone cancer, throat cancer, thyroid cancer, gastrointestinal cancer, cancers of the bladder and gallbladder, metastatic melanoma, and cancers in animals including feline, canine, and equine cancer. Keith Brewer, Otto Warburg, and H.E.Sartori all contributed to the concept of high pH therapy.

Cancerous tissues are acidic, whereas healthy tissues are alkaline. At a pH slightly above 7.4 cancer cells become dormant and at pH 8.5 cancer cells will die while healthy cells will live. Potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells. Glucose can still enter a cancer cell, but oxygen cannot. The cell thus becomes anaerobic. In the absence of oxygen, the glucose undergoes fermentation to lactic acid. The cell pH then drops to 7 and finally down to 6.5. cesium, rubidium and potassium, all having high pH values, are able to enter cells inthis state and raise their pH.

Acidity (nature of cancer cells) , is what cesium chloride treats primarily! 

Cesium is a very alkaline mineral (like Rubidium,Potassium and Calcium )! 

In particular, with regards to stopping the spread of cancer , cesium chloride is one of the best cancer treatments.

Cesium Chloride Protocol directly targets cancer cells. Normal cells do not ingest cesium chloride.


Cesium has been proven to get into cancer cells, when other nutrients can’t and:

1) makes the cancer cells alkaline (blood is not made alkaline, only inside the cancer cells)

2) limits glucose intake of cancer cells (starving them, thus making them ” sick ” due to lack of food),

3) neutralizes lactic acid (due to uncontrolled multiplication of cells) and, therefore cachexia cycle,

4) stops the fermentation ( side effect on glucose limitation).

The theory behind anti-cancer treatment cesium site is largely the result of Dr. A. Keith Brewer, PhD.


Excerpts from „The High pH Therapy for Cancer Tests on Mice and Humans”

Steps Leading to the Formation of Cancer Cells:

1. Glucose can still enter the cell, but oxygen cannot. The cell thus becomes anaerobic.

2. In the absence of oxygen, the glucose undergoes fermentation to lactic acid. The cell pH then drops to 7 and finally down to 6.5.

3. In the acid medium the DNA loses its positive and negative radical sequence. In addition, the amino acids entering the cell are changed. As a consequence, the RNA is changed and the cell completely loses its control mechanism. Chromosomal aberrations may occur.

4. In the acid medium the various cell enzymes are completely changed into very toxic compounds. These toxins kill the cells in the main body of the tumor mass. A tumor therefore consists of a thin layer of rapidly growing cells surrounding the dead mass. The acid toxins leak out from the tumor mass and poison the host. They thus give rise to the pains generally associated with cancer.

Mass spectrographic and isotope studies have shown that potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells. This uptake was enhanced by Vitamins A and C as well as salts of zinc and selenium. The quantity of cesium taken up was sufficient to raise the cell to the 8 pH range, where cell mitosis ceases and the life of the cell is short.

Tests on mice fed cesium and rubidium showed marked shrinkage in the tumor masses within 2 weeks. In addition, the mice showed none of the side effects of cancer.

In tests on mice, tumors implanted where significantly smaller at the end of the test in mice fed Rubidium than the controls. In addition, the test animals were showing none of the adverse effects of having cancer. Similar experiments with cesium chloride had similar successful results.

Tests have been carried out on over 30 humans. In each case the tumor masses disappeared.

Also, all pains and effects associated with cancer disappeared within 12 to 36 hours.

The more chemotherapy and morphine the patient had taken, the longer the withdrawal period.

Many tests on humans have been carried out by H. Nieper in Hannover, Germany and by H. Sartori in Washington, DC.

It has been observed that all pains associated with cancer disappear within 12 to 24 hours.

In these tests 2 gram doses of Cesium Chloride were administered three times per day after eating. In most cases 5 to 10 grams of Vitamin C and 100,000 units of Vitamin A, along with 50 to 100 mg of zinc, were also administered. Nieper and Sartori were also administering nitrilosides in the form of laetrile. There are good reasons to believe that the laetrile may be more effective than the vitamins in enhancing the pickup of cesium by the cells.

In addition to the loss of pains, the physical results are a rapid shrinkage of the tumor masses.

The material comprising the tumors is secreted as uric acid in the urine; the uric acid content of the urine increases many fold.

About 50% of the patients were pronounced terminal, and were not able to work. Of these, a majority have gone back to work.

Two side effects have been observed in some of the patients.

These are first nausea, and the second diarrhea. Both depend upon the general condition of the digestive tract.

There are a number of areas where the incidences of cancer are very low:

The Hopi Indians of Arizona have a very low incidence of cancer: 1 in 1000 as compared to 1 in 4 for the USA as a whole. Analysis of their diet shows that it meets the requirements for the high pH therapy. Hopi food is very high in potassium and exceptionally high in rubidium. Since the soil is volcanic it must also be very rich in cesium.

Some 20 years ago the incidence of cancer among the Pueblo Indians was the same as that for the Hopi Indians, but they have adopted a modern American diet and now have the same cancer rate as the rest of the US. Supermarket foods is essentially lacking rubidium and cesium and low in potassium.

The same, Hunza of North Pakistan and their diet also meets the requirements of the High pH therapy. They are essentially vegetarians, and are great fruit eaters, eating ordinarily 40 apricots per day; they always eat the kernels(laetrile), either directly or as a meal. They drink at least 4 liters of mineral spring waters which abound in the area and has been found to be very rich in cesium. Since the soil is volcanic in nature, it must be concluded that it will be rich in Cesium and Rubidium, as well as Potassium.

The Indians of Central America and on the highland of Peru and Equador also have very low incidences of cancer. The soil in these areas is volcanic with fruit in the area very high in rubidium and cesium.

Cases have been reliably reported where people with advance inoperable cancer have gone to live with these Indians, and found that all tumor masses disappear within a very few months. Clearly the food there meets the high pH requirements.

At the 1978 Stockholm Conference on Food and Cancer it was concluded that there is definitely a connection between no cancer and high PH theraphy(food+ alkaline minerals:calcium Cesium , Rubidium,Potassium.

Cesium and Rubidium salts, when present in the adjacent fluids, the pH of cancer cells will rise to the point where the life of the cell is short, and that they will also neutralize the acid toxins formed in the tumor mass and render them nontoxic.

Studies of the food intake in areas where the incidences of cancer are very low showed that it met the requirements for the high pH therapy.

Cesium, rubidium and potassium cations (positively charged ions) are all strong electron receptors which can be attracted into the membrane because of the negative potential gradient which exists across all living membranes.

The ready uptake of cesium and rubidium by the cancer cells lead the writer to the High pH therapy. This consists of feeding the patient close to 6 g of Cesium Chloride or Rubidium Chloride per day . It is sufficient however to give rise to the pH in the cancer cells, bringing them up in a few days to the 8 or above where the life of the cell is short. In addition, the presence of Cesium and Rubidium salts in the body fluids neutralizes the acid toxins leaking out of the tumor mass and renders them nontoxic.

In later writing, Dr. Brewer wrote: „The goal of the high pH therapy is the transport of large quantities of Cs+ Rb+ and glucose-free K+ across the membranes of cancer cells. During high pH therapy, Dr. H. Nieper, M.D., observed a loss of potassium which should be replaced.” Two booklets discussing Dr. Brewer’s final theories about cesium are available from the Brewer Science Library: „High pH Cancer Therapy with Cesium,” and „Cancer Its Nature and a Proposed Treatment,” both by A. Keith Brewer, Ph.D.


Mass spectrographic and isotope studies have shown that potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells.

Rubidium is an alkaline trace mineral related with cesium and potassium chemically. In cancer cells, only water, sugar, potassium, cesium and rubidium are able to enter the cells, therefore rubidium is one on the minerals used in high pH therapy. In studies with mice, rubidium has helped decrease tumor growth.

Germanium improves oxygen flow to tissues, boosting circulation, which improves stamina and endurance. It also has antioxidant properties.

Potassium is necessary for the transmission of nerve impulses that provide smooth coordinated muscle movement. Potassium also helps widen the blood vessels during exercise, thereby increasing blood flow to help carry away heat, and it is used to convert blood glucose to glycogen.           

Potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells. Glucose can still enter the cell, but oxygen cannot. The cell thus becomes anaerobic. In the absence of oxygen, the glucose undergoes fermentation to lactic acid. The cell pH then drops to 7 and finally down to 6.5. cesium, rubidium and potassium, all having high pH values, are able to enter cells inthis state and raise their pH.

Information Sources:

Elements below potassium in the Electromotive Series, like calcium, are only taken up sparingly, if at all, by cancer cells.

Therefore potassium, which transports glucose, can readily enter cancer cells, but Calcium, which transports oxygen, cannot.

Dr. Brewer used the powder of ionic cesium, not a liquid form , thus has not been as effective as compared with liquid  ionic cesium chloride.

The key difference is how big the group of cesium atoms are. If a group is too large (often met with powdered versions), cesium does not penetrate inside the cancer cells. Cesium simply does not work unless it enters within cancer cells.

Liquid ionic cesium chloride makes cancer cells highly alkaline (pH> 8.0) so that the immune system attacks them and kills them (thinking they are sick).

Tehnically, cesium chloride does not directly kill cancer but allows immune system to destroy cancer cells.

Yet probably, cesium chloride recovers normal cells from cancer cells(as  cancer microbes cannot survive in higly alkaline environment and once they die due to alkalinity, nothing prevents a cell from creating normal ATP energy) . This is  the ideal way to cure cancer because of low toxicity to the body

Cesium chloride not only kills cancer cells , it immediately stops the metastasis of cancercan start shrinking tumor masses within weeks , and almost always stops the pain within 24 to 48 hours, depending of the pain.

 „Many human trials have been carried out by [late] Dr. H. Nieper in Hannover, Germany, … as well as a number of other physicians Overall, the results were satisfactory Oart f .. He noted that all pains associated with cancer disappear between 12 and 24 hours, except in very few cases where there were problems of morphine waiver, which requires a few more hours. „

Many celebrities and executives in America went to Germany to be treated by Dr. Nieper, including a U.S. president. Dr. Nieper died in 1998.

Cesium treatment achieved a cure rate of 50% in patients with very advanced cancer, some already in a coma. 47 of the 50 patients were „hopeless” and some had only days to live .Doctors have given very high doses of cesium .


Excepts from „Cesium Therapy in Cancer Patients”

Treatment was performed on 50 patients during the last three years at Life Sciences Universal Medical Clinics in Rockville MD and in Washington D.C. All patients were terminal subjects with generalized metastatic disease. 47 of the 50 patients studies had received maximal modalities of treatment, i.e., surgery, radiation, and various chemotherapy, before metabolic Cesium-treatment was initiated. Three patients were comatose and 14 of the patients were considered terminal due to previous treatments outcome and cancer complications.

The Cesium-treatment was given in conjunction of other supportive compounds under diet control in addition to the utilization of specific compounds to produce adequate circulation and oxygenation. According to individual cases Cesium Chloride was given at daily dosages of 6 to 9 grams in 3 equally divided doses, with vitamin A-emulsion (100,000 to 300,000 U), vitamin C (4 to 30 grams), zinc (80 to 100 mg) selenium (600 to 1,200 mcg) and amygdalin (1,500 mg) in addition to other supplementations according to the specific needs of the patient. The diet consisted mainly of whole grains, vegetables, linolenic acid rich oils (linseed, walnut, soy, wheat germ) and other supplemental food. To increase efficiency of the treatment and improve the circulation and oxygenation, the patients received the chelating agent EDTA, dimethylsulfoxide (DMSO) and also a combination of vitamin K and Mg salts.

The 50 cancer patients studied over 3 years had generalized metastatic disease, except for 3 patients. Initial death occurrences for the initial 2 week treatment was in the same order and magnitude of these recorded for the 12 month period. The percent of survival of breast, colon, prostate, pancreas, and lung cancer accounted to approximately, 50% recovery which was higher than that noted for liver cancer and the lymphoma patients treated. An overall 50% recovery from cancer by the Cesium-therapy was determined in the 50 patients treated. Data from the autopsy made indicated the absence of tumors in patient dying within 14 days of the Cesium-treatment. One of the most striking effects of the treatment was the disappearance of pain in all patients within 1 to 3 days after initiation of the Cesium-therapy.

These studies were performed under my direction, initiated in April, 1981.

Twenty-eight patients were initially treated with Cesium Chloride between April, 1981 to October, 1982. They were subjected to various cancer therapies, e.g., surgery, radiation, and chemotherapy, and were considered terminal cases with metastatic disease except for 3 patients who were not previously treated. Three patients were comatose at the time of the Cesium treatment. Thirteen patients died within less than 2 weeks of treatment. Each patient showed a reduction in tumor mass by the Cesium-treatment. Of the breast cancer patients, the most impressive effect was seen on a female patient who was comatose at the beginning of the Cesium-treatment and was considered a terminal case. The Cesium-therapy, with other ingredients used, was immediately instituted by nasogastric route because there was no cooperation from the patient. The daily Cesium Chloride dose given amounted to 30 grams, 10 grams given 3 times daily. The patient was able to leave after 5 days of treatment. However the patient’s fall on the floor resulted in complications, i.e., fracture of the neck, and death. The autopsy revealed that the cancer metastasis had essentially eaten away her hip bone causing this tragic accident. The autopsy performed also showed the presence of very little cancer tissue.

The next most frequent cancer treated was of unknown primary.

Treatment of 8 cases showed a death rate of 2 within 14 days of treatment and an additional 2 deaths within 12 months while 4 of the patients are still living. In one case, an autopsy was made in a patient after one week of Cesium-treatment and showed a complete disappearance of the cancer. There were 7 cases of colon cancer patients who were treated with Cesium Chloride. Two of these patients died within 14 days, one of the patients had previous massive chemotherapy, and little time was available to restore her metabolic condition. The previous existing infiltration of the abdominal wall disappeared. However, no consent was given for an autopsy.

In one lymphoma case the patient displayed an unusually large abdomen which was hard and he weighed approximately 250 pounds. The massively enlarged abdomen began to decline in volume, i.e., a loss of approximately 120 pounds of body weight was noted after 3 months of the Cesium- therapy. The spleen which was originally maximally enlarged and reaching into the pelvis was reduced to almost normal size. The liver position was down to about the level of the umbilicus and was also reduced to normal size in 3 months. The patient is still living after 3 years after his discharge. Unfortunately, there is no follow-up on this patient and he is being maintained on chemotherapy.

The results presented demonstrate the rate of efficacy of Cesium Chloride in cancer therapy.

The total 50 TERMINAL cancer cases studied show an impressive 50% survival rate. This confirms the work of Messiha reported in these proceedings showing that the higher the dose it is, the more effective it seems to be. The autopsy obtained from the patient whose death was attributed to traumatic fracture of the neck, indicated that cancer had been initially further advanced resulting in bone destruction. However, the absence of cancer after the massive Cesium Chloride dose used in this case is demonstrable of the Cesium-therapy. It appears that both dosage, i.e., as much as 30 grams/day and route of drug administration, i.e., nasogastric pathway, might have contributed to the patients rapid recovery. It should be noted, however, that Cesium Chloride dose regimens should no exceed 20 to 40 grams due to side effects, mainly nausea, and diarrhea. The authors personal experience with Cesium Chloride after an acute dose of 40 prams Cesium Chloride indicate that extensive nausea and parethesia around the mouth are the major side effects. This is probably due to K depletion. The usual dose used in the clinic ranges from 2 to 3 grams given by mouth 3 times daily. At a later time, at which time there is no indication of cancer presence, the Cesium Chloride dosage will be reduced to a preventative dose between .5 and 1 gram a day.

The lymphoma case presented shows that Cesium Chloride efficiently reduced massive enlargements of spleen and liver as well as maximal ascites, causing an abdominal configuration of a tight, hard hemisphere, to almost normalize after 3 months of therapy. This period of time was required to eliminate such a massive volume resulting in the reduction of the body weight noted.

The clinical efficacy of Cesium Chloride high pH metabolic therapy is best demonstrated by a recent case of primary liver cancer (not included in the 50 cases reported in this study). The patient was a 39 year old female teacher who was terminal. She was brought on a stretcher on April 25, 1984 with a large liver tumor extending approximately 3 cm below the umbilical level. The treatment was then immediately instituted. This consisted of administration of Cesium Chloride, Beta-carotene, Vitamin C, Zn, Se, Mn, Cr, and K salts by the oral route in addition to a concomitant massive IV doses of ascorbate, K, Mg, Zn, Cn, Mn, Cr salts, B complex vitamins, folic acid, DMSO and heparin. After 5 consecutive treatment regimens EDTA was introduced to the therapy and the minerals present in the solution were discontinued. On May 10, 1984, the patient was discharged, returned home walking without assistance and displaying a smile on her face. The liver tumor had shrunk to 5 cm above the umbilicus. The determination of alphafetoprotein (AFP), a specific marker for liver cancer, rare embronal cancer and teratomas, decreased from the unusually high value of 39,000 units, compared to normal levels of 13 units, measured before initiation of Cesium-therapy, to 5000 units obtained on the last day of treatment.

The mechanism of action of Cesium in cancer has been little studied. That both Cs+ and Rb+ can specifically enter the cancer cells and embryonic cells but not normal adult cells has been demonstrated by Brewer. The cancer cells contain high amounts of hydrogen ions rendering them acidic and they also contain high Na+ levels than found in normal cells. If Cs+ or Rb+ can enter the cancer cells then the pH increases from as low as 5.5 to over pH 7.0. At a pH of 7.6 the cancer cell division will stop, at a pH of 8.0 to 8.5 the lifespan of it is considerably shortened (only hours). In one case, the author has observed the shrinkage of metastases of breast cancer after one hour of Cesium-treatment. Two days later wrinkles of the skin appeared where the tumor was present. In another case of a colon cancer with massive metastasis, of massive infiltration of the abdominal wall, liver and other tissues, seemed to have been reduced within 24 hours and continuing rapidly until the demise of the patient on the 14th day of the Cesium-treatment.

The uric acid levels measured at the onset of treatment was approximately 3.5 units which was increased to over 20 units, suggesting massive breakdowns of DNA, which produces the uric acid output. Therefore, destruction of nuclear acids, as reflected by a significant rise in the uric acid, may be used as a predictive measurement for treatment outcome. The failure of uric acid elevation may be indicative of lack of destruction of cancer cells. This has proven to be a very consistent finding in our clinic.

MORE ON CESIUM as well as a POWERFUL(STAGE IV) cancer treatment in my book.

You can find Robert R. Barefoot Cesium Chloride Protocol that he mentions in this book in chapter 17. If you do use this protocol it would be the ethical thing to do to buy his book. You will learn a lot about calcium also in his book, and also heart disease.


There is an ample bibliography about organic Germanium: 107, 110, 119, 139, 174, 193, 237, 249, 269, 336, 357, 386, 399, 440, 441, 460, 476).for studies cited above see last page of database.

SEE also: Mainwaring MG: Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide, Chest, 117, pp. 591-593, 2000; Chest, 117, pp. 307-308, 2000 

Organic and inorganic forms of Germanium

For any therapy, only very pure organic Germanium should be used. The heavy metals (Pb, As, Hg, Cd) should be almost absent, and if they are present should only be in well defined and negligible  quantities (<0,1ppm); moreover there must be no traces of Germanium oxide (GeO2).

Inorganic Germanium is toxic for the kidney cells.In its inorganic from Germanium is present in the soil, rocks and coal, together with other minerals from which it can be extracted and transformed industrially into organic Germanium.

Natural organic Germanium

Organic Germanium is found naturally in Allium sativum, Allium cepa, Panax ginseng, Pfaffia paniculataOrganic Germanium is found naturally in some oriental mushrooms: Ganoderma lucidum, Grifola frondosa  but this are dangerous

The immune stimulating properties of organic Germanium

The most important property manifests itself in the stimulation of the immune system.

Especially with regard to the Natural killers, the increase in cytolytic ability already begins from the second day, reaching its peak on the fourth day, finally exhausting itself a week from the last  administration; an increase of 30% can be seen in the cytolysis, compared to control groups treated  with a placebo.

Studies on the anti-cancer effect of Germanium have also shown the role it plays in activating the T lymphocytes, the macrophages, the lymphokines and Gamma interferon: Germanium stimulates the T lymphocytes to produce lymphokine, MIF (Migration Inhibition Factor), MAF (Macrophage Activation Factor), chemotactic factors, CSF (Colony Stimulating Factors) and lymphotoxins.

The subsequent Immune Cascade also establishes an activation of the macrophages which take part in the lysis of the cancer cells in an effective ratio of 1:1, like cytotoxic T lymphocytes, Natural killers and Killers. On the other hand,NO activation of the granulocytes has been shown, but the more difficult capacity for anti-cancer activation is known,  which requires a strength ratio of 40:1 between the granulocytes and the cancer cells.

Anti-oxidant property of organic Germanium

The specific action of Germanium 132 is on a biochemical level, since it renders oxygen available for the cells, with the important implications therefore for cancer. Among these are a large number of degenerative pathologies, pathologies of the metabolism  or caused by some deficiency. In particular, its biochemical characteristic is that it acts as a semiconductor  in the transport processes of the electrons inside the cells, thus allowing the formation of ATP with the final production of non toxic molecular substances (water). Its anti-oxidant actionagainst cysteine is also important.

Cell respiration refers to the catabolic processes by means of which the nutritive substances, glucose for example, are broken up inside the cells, releasing energy which is then used to form Adenosine-Tri-Phosphate (ATP, cell energy).

With organic Germanium an exothermic reaction takes place, which supplies oxygen and hydrogen to the individual cells of the organism. The stable  and continuous flow of oxygen and hydrogen to all parts of the organism facilitates and strengthens oxidation and reduction inside the cells: oxidation takes place either with the acquisition of oxygen or with the loss of hydrogen.

Any reaction which creates energy inside a cell is an oxidant reaction.

Oxidation can happen in two ways:

1) the combination of oxygen with other elements

2) the removal of hydrogen atoms from the compounds.

Basically, oxidation of nutritive substances is the gradual removal of pairs of hydrogen atoms from the support molecules, because when the pairs of hydrogen atoms are removed, they take with them their electron pairs. In this way oxidation of glucose in Krebs’ cycle occurs with the gradual  removal of hydrogen atoms.

Where a substance loses electrons, becoming oxidated and losing energy, there is another substance which acquires them, thus becoming reduced, that is to say, acquiring energy.

The hydrogen atoms which are removed are sent to the  electron transport chain, which converts the energy taken from the oxygen, to transport the electrons along the whole length of the chain.

In the end the hydrogen atoms which are removed combine with the molecular oxygen (creating water), and the resulting energy is freed as ATP, and thus available for the cells.

The immune cells, such as the very delicate lymphocytes, thus acquire an energy capacity which enables them to do their work even in a hypoxic environment such as cancer tissue, famously characterized by High Interstitial Fluid Pressure (H.-I.F.P. see: see: Jain R.K.: Barrier to Drug Deliver y  in Solid Tumors, Scientific American, Science, July,1994). Vice versa the cancer cells, which have become oxidated both because of the removal of hydrogen and also by the endocell molecular reaction with oxygen, both induced by the presence of organic Germanium, as a result are more exposed to the phenomena of apoptosis and pseudo-apoptosis, being poor in enzymatic complexes which would perform an endo-nuclear repair of their own DNA, which on the contrary are characteristic of normal cells which have not been degenerated by cancer.

Anti-ischemic properties of organic Germanium

It acts as an electro-nutrient in hypoxic states, which are frequent in chronic degenerative pathologies, such as cardio-vascular or neuro-vascular pathologies or those of the metabolism in general.

Organic Germanium stimulates the ability to increase the availability of oxygen for the cells and helps eliminate unpaired electrons. This makes it particularly invaluable in cases of acute ischemia (miocardic infarct, strokes and asphyxiation by carbon monoxide).

Modifications of the biochemical and functional parameters of the organism induced by organic Germanium

The catalytic effects on the use of oxygen are seen in the renormalization of the biochemical and functional parameters of the organism in a time-frame of between 4 to 6 weeks:

1) Regularization of the partial pressure of carbon dioxide in the blood.

2) Regularization of the values of hematic glucose, above all in diabetic patients.

3) Reduction of the triglycerides.

4) Regularization of total cholesterol with an increase in the ratio of HDL/LDL.

5) Normalization of bilirubin.

6) Normalization of uric acid.

7) Regularization Na / K, Ca / Mg.

8) Increase in haemoglobin.

9) Lymphocite rebalance in chronic infectious diseases. (HIV/AIDS).

10) Protection from oxidative damage induced on the DNA by ionizing radiation.

Anti-amyloidosis property of organic Germanium

Amyloidosis is often induced by Chemo-Therapy or radio-therapy.

Germanium protects against the accumulation of amyloid substances, a process which is generated by a protein imbalance in the catabolism and often associated with chronic inflammatory conditions.

Analgesic property of organic Germanium

Organic Germanium has analgesic effects, acting as a neuro-modulator. This happens through the inhibition of enzymes (peptidase such as Aminopeptidase, Carboxypeptidase, dipeptidil- Aminopeptidase and dipeptidil-Carboxypeptidase [also known as Enkefalinase B and D]) which downgrade the endorphins.

Since it is difficult to find natural organic Germanium, and it is very expensive, the following proposal could be useful: to use inorganic Germanium (which is much less expensive than organic Germanium) in the cultivation of plants with a great capacity for trace-mineral uptake. The cultivation of Equisetum arvense, Medicago sativa, Rosmarinus officinalis and Aloe arborescens could be particularly useful.


(NaturalNews) If you or a woman close to you were advised to have a double mastectomy performed in order to prevent breast cancer, shouldn’t another option be available? Medical mutilations have been performed lately on women told they are genetically predisposed to getting breast cancer.

That other option could be a good diet with supplemental iodine. Exactly why iodine offers the other option for preventing breast cancer regardless of genetics is referenced later in this article.

Dr. David Brownstein could be called Dr. Iodine for all he’s done to inform others of the importance of iodine through interviews and his book Iodine: Why You Need It; Why You Can’t Live Without It.

Dr. Mark Sircus, who occasionally contributes articles to Natural News, constantly promotes bicarbonate of soda, magnesium, and iodine as more important and effective for health than most realize.

Now, Dr. Jeffrey Dach has grabbed the iodine talking stick, producing several international clinical, lab, and case study reports that demonstrate the efficacy of iodine ingestion for breast cancer.

Dr. Dach on iodine

Salt used to be iodized with elemental iodine to prevent goiter, but no more. So what little protection that offered has vanished. Dr. Dach notes that iodized salt is not sufficient for supplementing iodine.

Iodine’s RDA (Recommended Dietary Allowance) is 150 mcg (micrograms) per day. Dr. Guy Abraham, who initially mentored Dr. Brownstien, insists we should be taking in 12.5 mg (milligrams) of elemental iodine daily. This is 100 times greater than our RDA.

It’s also the estimated iodine per individual intake from seaweed and seafood among Japan’s population. Japan has the lowest rates of thyroid, prostate, and breast cancer. Some might argue that the Japanese get their iodine from food, but iodine supplements are unsafe.

Well, the FDA recommends 165 mg of iodine to prevent thyroid cancer in the event of a radiation emergency, and iodine has been used medicinally with even higher doses in the past.

Speaking of thyroid cancer, there has been an upsurge of thyroid nodules, leading to complete removal of thyroid glands to determine whether the nodules are cancerous.

Some biopsy! Even if no cancer is detected, the person is sentenced to a lifetime of synthetic prescription thyroid hormones. Iodine can prevent that unhealthy scenario.

In addition to preventing some cancers, there are several studies and actual case histories demonstrating iodine’s ability to cure breast cancer.

Lab studies and breast cancer case histories

Here’s that option for stemming genetically predisposed breast cancer. Iodine has been determined to actually alter breast cancer associated gene expressions. It turns off cancer promoting genes and turns on genes that promote cancer cell apoptosis or cellular destruction. (

Another study proves that large iodine intake does not adversely affect thyroid hormone production or quality. The researchers did this to allay concerns in the medical profession about potential downsides for using iodine against breast cancer. Downsides don’t prevent using chemo and radiation though.

Dr. Dach lists many international in vivo studies using rats, epidemiological human surveys, and in vitro (petri dish) lab studies demonstrating the efficacy and safety of ingesting elemental iodine for cancerous tumors. All of these studies, with a few actual case histories, are available in Dr. Jeffrey Dach’s articles sourced below:

Dr. Guy Abraham developed a product called Idoral. And Dr. Edward Group, DC, ND, lists four types of iodine supplements that vary in bio-availability: Nascent iodine, Lugol’s solution, potassium iodide, and transformative nano-colloidal detoxified iodine.

The cancer industry’s willful denial of iodine for breast cancer is not because it’s ineffective and dangerous. It’s because supplemental iodine can’t be patented.
Iodine alters gene expression in the MCF7 breast cancer cell line: evidence for an anti-estrogen effect of iodine. 2008 International journal of medical sciences
A prospective study of Iodine status, thyroid function, and prostate cancer risk: follow-up of the First National Health and Nutrition Examination Survey.…/1709128_Use_of_Lugols_iodine_in_oral_cancer _diagnosis_an_overview.html

Studies on Iodine and Apoptotic


One of the most effective naturally occurring weapons against cancer is, like most healthy things, something many of us are not getting enough of. The mineral selenium has been shown in multiple studies to be an effective tool in warding off various types of cancer, including breast, esophageal, stomach, prostate, liver and bladder cancers. Not many people get the recommended dose of 200 micrograms a day. Most Americans only get between 60 and 100 micrograms of selenium daily from dietary sources, according to the Life Extension Foundation’s Disease Prevention and Treatment. That means daily supplements might be worth considering.

Selenium was first used in conventional medicine as a treatment for dandruff, but our understanding of the mineral has come a long way since then. Today, research shows selenium, especially when used in conjunction with vitamin C, vitamin E and beta-carotene, works to block chemical reactions that create free radicals in the body (which can damage DNA and cause degenerative change in cells, leading to cancer).Selenium also helps stop damaged DNA molecules from reproducing. In other words, selenium acts to prevent tumors from developing. „It contributes towards the death of cancerous and pre-cancer cells. Their death appears to occur before they replicate, thus helping stop cancer before it gets started,” says Dr. James Howenstine in A Physician’s Guide to Natural Health Products That Work.

Selenium & Chemotherapy

In addition to preventing the onset of the disease, selenium has also been shown to aid in slowing cancer’s progression in patients that already have it. According to the Life Extension Foundation, the use of selenium during chemotherapy in combination with vitamin A and vitamin E can reduce the toxicity of chemotherapy drugs. The mineral also helps „enhance the effectiveness of chemo, radiation, and hyperthermia while minimizing damage to the patient’s normal cells; thus making therapy more of a ‘selective toxin,'” says Patrick Quillin in Beating Cancer with Nutrition.A 1996 study by Dr. Larry Clark of the University of Arizona showed just how effective selenium can be in protecting against cancer. In the study of 1,300 older people, the occurrence of cancer among those who took 200 micrograms of selenium daily for about seven years was reduced by 42 percent compared to those given a placebo. Cancer deaths for those taking the selenium were cut almost in half, according to the study that was published in the Journal of the American Medical Association.While the study concluded the mineral helped protect against all types of cancer, it had particularly powerful impacts on prostate, colorectal and lung cancers. Jean Carper, in Miracle Cures, called Dr. Clark’s findings an „unprecedented cancer intervention study” that „bumped up the respectability of using supplements against cancer several notches.”

Food Sources:

Although too much selenium can actually be toxic to the system, research indicates the majority of the population is not getting enough of the essential mineral. So, how can we up our intake of selenium and help our bodies fight cancer? The good news is there are some good dietary sources of selenium: Mushrooms, egg yolks, seafood, poultry and kidney, liver and muscle meats contain the mineral. Vegetables – garlic, onions, broccoli, asparagus, tomatoes and others – as well as whole grains and seeds can also be good sources of selenium.However, because the amount of selenium in vegetables and grains depends on the selenium content in the soil in which they are grown, it can be hard for average consumers to know how much of the mineral they are actually getting in their diets. „The selenium content of food is largely dependent on the content of volcanic ash in the soil on which the food was grown, with higher volcanic ash content yielding higher selenium levels. Soil that is irrigated by seawater, such as much of California’s cropland, also contains higher levels of selenium,” says Sue Gebo in What’s Left to Eat. Gebo adds that, in general, soil in the western United States is richer in selenium than soil in the eastern part of the country.Accordingly, geography can have a significant impact on diet. In Antioxidants Against Cancer, author Ralph Moss PhD, says one theory for why cancer rates are so high in Linxian, China, dubbed „the ‘world capital’ of cancer,” is that the soil is deficient in the essential minerals selenium and zinc. In Earl Mindell’s Supplement Bible, Earl Mindell RPh PhD, suggests part of the reason American men are five times more likely than Japanese men to die from prostate cancer could be because, in general, „the Asian diet contains four times the amount of selenium as the average American diet.”Another reason it seems to be difficult for Americans to get enough selenium is the processing many of our foods go through before they make it onto grocery store shelves. Mindell points out, for example, that processing wheat into white flour strips it of a great deal of its selenium. One way to get more selenium in your diet might be to eat more organically grown foods, which some studies have shown to contain more selenium as well as higher levels of beta carotene and vitamin E. These two work together with selenium in cancer prevention, according to Alternative Medicine author Burton Goldberg.Perhaps a more surefire way to boost your selenium intake is to add supplements to your diet. Mindell advocates the use of supplements, saying, „To me, taking selenium supplements, in addition to eating selenium-rich foods, is good insurance against disease.” However, for those who oppose taking pills, Dr. Andrew Weil in Ask Dr. Weil says eating just one shelled Brazil nut – grown in the selenium-rich soil of central Brazil – provides 120 micrograms of the mineral, getting you that much closer to the daily target of 200 micrograms.Although extremely high doses of selenium can have toxic effects, most people are not at risk for such an overdose, and could, in fact, use more of the mineral. Simply adding more selenium-rich foods, such as organically grown vegetables and fruits to your diet, along with supplements, can help reduce your risk of cancer. And another positive side effect of selenium, according to Eat and Heal, by the Editors of FC&A Medical Publishing, is that it can actually improve your mood. Those editors write, „People who don’t eat enough selenium-rich foods tend to be grumpier than people with a high dietary intake, according to recent research.” So, go ahead and crack a Brazil nut open and smile.The experts speak on selenium and cancer

Selenium Mechanisms

There are several possible mechanisms for the protective effect of selenium. Selenium activates an enzyme in the body called gluthathione peroxidase that protects against the formation of free radicals—those loose molecular cannons that can damage DNA. In this situation, selenium may work interchangeably (and in synergy) with vitamin E. In test tube studies, selenium inhibited tumor growth and regulated the natural life span of cells, ensuring that they died when they were supposed to instead of turning „immortal” and hence malignant. Because of this particular action, the University of Arizona researchers say that selenium could be effective within a fairly short time frame. 
Ask Dr Weil by Andrew Weil MD, page 207

Numerous studies suggest that an inverse association exists between selenium levels and cancer incidence (Hocman, 1988; Willett and Stampfer, 1986; Milner, 1985). Associations appear to be particularly strong with cancers that are also associated with high-fat, low-fiber diets (i.e., breast, colon, prostrate, etc.). The mechanism for selenium’s reported protective effects is likely due to its function in antioxidant synthesis. Glutathione peroxidase, the primary enzyme that converts hydrogen peroxide to water (and thus prevents lipid peroxidation) is selenium-dependent. Inhibition of lipid or bile acid oxidation may account for its protective role (reviewed by Linder 1991:496-7). Selenium may also act as an immune stimulant. Selenium deficiency inhibits macrophage-mediated tumor destruction, and inhibits tumor necrosis factor-alpha production in animals (Kiremidjian-Schumacher et al., 1992). Dietary supplementation with selenium produced the opposite effects.
Cancer And Natural Medicine by John Boik, page 146

The safest antioxidants are vitamin C, vitamin E, selenium, and beta-carotene. Together, they block the chemical reactions that create free radicals, which can damage DNA and promote a variety of degenerative changes in cells. Chemotherapy and radiation generate free radicals; that is how they kill dividing cells.
Ask Dr Weil by Andrew Weil MD, page 47

At the Yunnan Tin Corporation in China there is a very high rate of lung cancer among the miners. Forty healthy miners were given selenium supplements for a year. The selenium, which increased in their blood, boosted a key detoxifying enzyme system while simultaneously decreasing dangerous lipid peroxide levels by nearly 75 percent. It also protected against cancer-causing substances and ultraviolet radiation. Doctors at the Chinese Academy of Medical Sciences concluded that selenium supplements were a safe and effective food supplement for people.
Cancer Therapy by Ralph W Moss PhD, page 112

Numerous mechanisms have been explored to explain the modulation of carcinogenesis by selenium (Medina 1986, El-Bayoumy 1991). The best characterized function of selenium in mammalian cells is as a component of the seleno- enzyme, glutathione peroxi-dase. This enzyme is localized in the cytosol and mitochondrial matrix, and it eliminates organic peroxides from the cell (Medina 1986). However, available evidence suggests that the prevention of carcinogenesis by selenium is not related to its function in glutathione peroxidase (Medina 1986). Other seleno- proteins have been identified, but their impact on carcinogenesis is not defined (Medina 1986). There is some evidence that selenium may alter the metabolism of carcinogens or the interaction of chemical carcinogens with DNA, but there is considerable controversy in the literature (Medina 1986). Additional mechanistic studies suggest that selenium may alter cell proliferation and/or immunologic responses (Medina 1986, El-Bayoumy 1991). Further research is needed to understand the mechanisms whereby selenium prevents cancer.
Carcinogens Human Diet by National Research Council, page 100

Selenium is needed to produce glutathione peroxidase, an antioxidant enzyme that protects the body from free radical damage. It is also important in preventing cancer and cardiomegaly an enlargement of the heart that causes premature aging and early death.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 11

The best known functions of selenium at nutritionally adequate, but not at excessive, levels are its role as a part of the enzyme glutathione peroxidase and its interaction with heavy metals. Glutathione peroxidase destroys hydroperoxides and lipoperoxides, thereby protecting the constituents of the cells against free radical damage. Ip and Sinha (1981) have shown that selenium, through its function in glutathione peroxidase, could well be involved in protecting against cancer induced by high intakes of fat, especially polyunsaturated fatty acids. Glutathione peroxidase activity in human blood increases with increasing selenium intakes, but reaches a plateau at intakes well below those customary in the United States (Thomson and Robinson, 1980). Thus, if the antitumorigenic effect of selenium is mediated through its function in glutathione peroxidase, attempts to increase the enzyme activity by selenium supplementation, superimposed on an adequate diet in the United States, would not be successful. The second function of selenium is to protect against acute and chronic toxicity of certain heavy metals. Although selenium is known to interact with cadmium and mercury, the mechanism of action is not known. Selenium does not cause an increased elimination of the toxic elements, but, rather, an increased accumulation in some nontoxic form (National Academy of Sciences, 1971). It is conceivable that carcinogenic effects of these, and perhaps other heavy metals, could be counteracted by selenium, in a manner similar to its protection against their general toxicity.
Diet Nutrition Cancer by National Research Council, page 168

Selenium’s main function in the body is to convert hydrogen peroxide to water, which is important for cellular health. Herbal Medicine Healing Cancer by Donald R Yance Jr, page 193 All of the body’s tissues contain selenium, but it is most plentiful in the liver, kidneys, spleen, pancreas, and testes. Selenium works synergistically with vitamin E to protect tissues and cell membranes, aid in the production of antibodies, and help maintain a healthy heart and liver
Prescription For Dietary Wellness by Phyllis A Balch, page 44

Selenium Dosage/Administration

It has been reported that selenium doses of about 250-300 micrograms a day (diet and supplements) would be helpful in preventing cancer. If an average person consumes 125 to 150 micrograms of selenium a day, an additional supplemental amount of 100 micrograms is unlikely to produce any major side effects. 
Choices In Healing by Michael Lerner, page 612

Recommendation: Take selenium aspartate in a dose of 100 to 200 micrograms daily..
Doctors Complete Guide Vitamins Minerals by Mary D Eades MD, page 496

Selenium is a mineral with anticancer activity. But the anticancer effects of selenium are greatly reduced when there is an insufficient intake of vitamin E. Rats who receive a normal amount of vitamin E in their diets showed a 45 percent decrease in tumors when they were given selenium. But they only had a 25 percent decrease if their diet was low in vitamin E. In fact, vitamin E was considered more important than selenium in decreasing „oxidant stress” to the fat of the breast.
Cancer Therapy by Ralph W Moss PhD, page 74

In the treatment of cancer the dosage is generally about 10,000 micrograms, still nearly one hundred times the National Academy of Science’s recommended dose. Revici’s treatment is more complicated than just organic selenium. He only uses selenium in patients whom he deems to be in a „catabolic,” as opposed to an „anabolic,” state. He has devised a number of urine tests to find whether a patient is in one condition or the other. Selenium is given when the urine has a low specific gravity, a high surface tension and a pH above 6.0. The alkalinity of the urine is supposed to reflect the state of the body’s defenses against tumors.
Cancer Therapy by Ralph W Moss PhD, page 112

Selenium levels show a U-shaped correlation with prostate cancer. In other words, both low and high blood levels of selenium increase risk. This simply means that we need enough selenium to maintain good health, yet too much can be dangerous. A practical compromise is to use a supplement that provides 100 I.U. of vitamin E (up to 400 I.U. would be fine), and about 50 micrograms of selenium.
20 Natural Ways To Reduce The Risk Of Prostate Cancer By James Scala PHD, page 60

Unlike selenomethionine, which is incorporated into protein in place of methionine, SMSC is not incorporated into any protein, thereby offering a completely bioavailable compound. In animal studies, SMSC has been shown to be 10 times less toxic than any other known form of selenium. The recommended dose of Se-methylselenocysteine (SMSC) is 200-400 mcg a day for cancer patients.
Disease Prevention And Treatment by Life Extension Foundation, page 316

Selenium Sources

You need just three Brazil nuts to get the 200 micro-grams of selenium that studies have shown to have a potent anti-cancer effect. As a bonus, when you eat Brazil nuts, which grow best in the Amazon rain forest, you support the conservation of one of my favorite places on earth. So you’re not only protecting your body, you’re saving the environment. 
Anti-Aging Prescriptions by James Duke PhD, page 90

The Garlic Connection. It has long been noted that people who ate garlic, onion, broccoli, and whole grains had a reduced risk of cancer. It turns out that all of these foods are rich in selenium, in fact, selenium is one of the reasons that these particular foods are so healthful for us.
Antioxidants Against Cancer by Ralph Moss PhD, page 77

If you’re not fond of popping pills, you can get 120 micrograms of selenium in just one Brazil nut. Buy the shelled kind—they’re grown in a central region of Brazil where the soil is richest in the mineral. Other good sources are tuna fish, seafood, wheat germ, and bran.
Ask Dr Weil by Andrew Weil MD, page 207

One good food source is Brazil nuts, which happen also to contain at least one other anticancer substance, ellagic acid. One large nut can provide over 50 mcg of selenium. When Cornell scientist Donald J. Lisk and his colleagues ate six Brazil nuts a day for three weeks, their blood levels of selenium rose between 100 and 350 percent.
Cancer Therapy by Ralph W Moss PhD, page 122

Selenium—An essential trace mineral found in fruits and vegetables, selenium helps the body produce functional glutathione peroxidase, an enzyme essential for detoxification. Low dietary levels of selenium have been correlated with a higher incidence of cancer; accordingly, supplementation of this nutrient acts as a deterrent against cancer in general.
Alternative Medicine by Burton Goldberg, page 591

Red clover is also rich in calcium, manganese, and selenium, which is a key cancer-fighting antioxidant. I munch the flower heads, but not everyone likes them. Some people dry the flower heads, turn them into a powder, and add them to soups.
Anti-Aging Prescriptions by James Duke PhD, page 61

The debate continues regarding the active ingredients in garlic, but they may include amino acids (like the branched chain amino acids of leucine and isoleucine), S-allyl cysteine, allicin, and organically-bound selenium…Garlic grown on selenium-rich soil was more effective than selenium supplements at inhibiting carcinogen-induced tumors in animals. A study published in the Journal of the National Medical Association referred to garlic as „..a potent, non-specific biologic response modifier.”
Beating Cancer With Nutrition by Patrick Quillin, page 147

A particularly worthy form of selenium is Se-methylselenocysteine, currently available and attracting positive attention. This is the form of selenium found naturally in plants such as broccoli and garlic. A suggested selenium dosage (as a preventive) is 200 mcg a day. The optimal dose for the cancer patient is unknown at this time, but suggestions have ranged from 200-400 mcg a day. Depending upon the selenium content of the soil, foods considered to be good sources of selenium include Brazil nuts, grains, onions, tomatoes, broccoli, chicken, eggs, garlic, liver, seafood, and wheat germ. Americans typically get from 60-100 mcg of selenium a day from dietary sources.
Disease Prevention And Treatment by Life Extension Foundation, page 243

Stephen Cann, associate researcher at the University of British Columbia, gives advice to women who want to fight breast cancer with diet, „Eat different types of seaweed.” These include wakame, kombu, and the more common nori — sea vegetables that might fight cancer because of their iodine and selenium. „We think it’s very important for the breast,” Cann says about iodine. This mineral, he believes, may prevent and even shrink breast tumors by combining with certain fatty acids and stopping cancerous cells from multiplying. And without the selenium, iodine doesn’t do its job properly.
Eat and Heal by the Editors of FC&A Medical Publishing, page 317

In parts of Europe, pumpkin seeds are the standard treatment for benign prostate enlargement. The seeds are rich in zinc, selenium and other minerals that have been shown to reduce prostate cancer risk. Typical daily dosage: Eat one-quarter cup of the seeds.
Bottom Line Yearbook 2002 by Bottom Line Personnel, page 76

The intake of selenium and other nutrients from plant foods may be influenced by the type of farming practices used. In a preliminary investigation, organically grown foods were, in some cases, nutritionally superior to conventionally grown foods (Smith, 1993).
Cancer And Natural Medicine by John Boik, page 147

The Journal of Nutrition reported that selenium-enriched broccoli is protective against chemically induced mammary and colon cancer in rats (Davis et al. 2002). Note: While selenium is contributing to the lower incidence of malignancy, the anticancer affects of broccoli should also be factored into the defense.
Disease Prevention And Treatment by Life Extension Foundation, page 242

You can find selenium in grains, shellfish, poultry, garlic, and egg yolks.
Natural Cures And Gentle Medicines by The Editors of FC&A Medical Publishing, page 266

Commercial preparations of selenium include inorganic selenium (sodium se-lenite) and various organic compounds of selenium. It has been reported that sodium selenite is not absorbed adequately, whereas organic selenium, including yeast-selenium, is absorbed very well. For this reason, yeast-selenium is considered best for human consumption
Choices In Healing by Michael Lerner, page 612

Throughout history and around the world, people from Mexico to Russia have given mushrooms magical powers. In reality, there’s nothing miraculous about these fungi at all, but they can make you healthier. Although mushrooms are largely made up of water, they are also high in protein, carbohydrates, and fiber. They are a potent source of vitamin D, riboflavin, and niacin, plus minerals like potassium, selenium, and copper.
Eat and Heal by the Editors of FC&A Medical Publishing, page 252

In addition, some foods, such as lima beans, soy beans, and other soy products, seem to have medicinal capabilities because of the presence of isoflavones and phytoestrogens, or plant estrogens. These substances actually curb the activity of the excess estrogen in the body’s tissues. Phytoestrogens can also be found in other vegetables and in fruits, along with useful amounts of nonsoluble fiber, beta-carotene, and selenium.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 72

A new approach is now being explored: how to enrich our food with antioxidant and protective agents. The simpler approach is to add antioxidant vitamins to basic foods. Studies address the genetic engineering of food to prevent heart disease and cancer [105], and such measures as growing garlic with selenium fertilization [95]. The authors of these studies state that „in view of the impossible task of persuading the public to eat only those foods that are presumably good for their health . . . the time has come to enrich our foods with known cancer preventive agents so that their benefit can be realized fully over the life span of the individual.”
Every Persons Guide To Antioxidants by John R Smythies MD, page 103

Plentiful in poultry, selenium may help to protect against cancer, cataracts, heart disease, and macular degeneration. Dark-meat turkey is particularly high in this mineral (3 ounces of cooked turkey have 35mcg of selenium, or 50% of the Daily Value).
Fight Back With Food by Readers Digest, page 73

To get more selenium in your diet, try tuna; a three-ounce can serves up a full 99 micrograms. Or treat yourself to an ounce of baked tortilla chips for a whopping 284 micrograms.
Healing With Vitamins by Alice Feinstein, page 64

Selenium comes from the soil, and fruits and vegetables that come from selenium-rich soil are more likely to contain the mineral.
Natures Medicines by Gale Maleskey, page 363

If you eat a normal diet with plenty of unprocessed foods, you should be fine. You’ll find selenium in many grains, nuts, and vegetables; meat, especially organ meats like liver; and seafood.
Natural Cures And Gentle Medicines by The Editors of FC&A Medical Publishing, page 242

A new form of selenium is Se-methylselenocysteine (SeMC), a naturally occurring selenium compound found to be an effective chemopreventive agent. SeMC is a selenoamino acid that is synthesized by plants such as garlic and broccoli.
Disease Prevention And Treatment by Life Extension Foundation, page 277

Essiac formula was given to nurse Rene Caisse more than 80 years ago by a woman whose breast cancer had been healed by this Ojibway Indian herbal preparation. The formula is composed of four herbs (burdock root, slippery elm, sheep sorrel, and Indian rhubarb). The burdock root contains inulin, which improves the function of white blood cells. This root also contains Vitamin A and selenium, which scavenge free radicals and chromium which regulates blood sugar levels.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 156

Selenium Anti-Cancer Effects

Some forms of cancer are the result of free radical oxidation that destroys or damages the part of the DNA that regulates cell multiplication. When that happens, the cells can begin to multiply abnormally, damaging the healthy tissue until your whole body is invaded by these wildly proliferating cells. Since selenium can protect you from free radical oxidation, one way to minimize your risk of developing this type of cancer is to eat selenium-rich foods like whole grains or their products with each meal. If you already have cancer, selenium may be useful in slowing its progression. A way to get it in even more concentrated doses than in foods is to take brewer’s yeast or supplements. 
Complete Guide Health Nutrition by Gary Null, page 483

Laboratory studies have shown that selenium can inhibit the growth of breast, cervical, colon, and skin cancer.
Antioxidants Against Cancer by Ralph Moss PhD, page 79

Regular intake of yellow and green vegetables, as well as foods containing calcium, selenium and other micro-nutrients, lowers the risk of colon cancer.
Cancer Therapy by Ralph W Moss PhD, page 197

Selenium is protective against many types of cancers, promotes apoptosis, is a powerful antioxidant, and improves quality of life during aggressive cancer therapies According to P.D. Whanger (professor of agricultural chemistry), nearly 200 animal studies have been conducted to evaluate the effects of supernutritional levels of selenium on experimental carcinogenesis using chemical, viral, and transplantable tumor models. Two thirds of the studies found that high levels of selenium reduced the development of tumors at least moderately (14-35% compared to controls) and, in most cases, significantly (by more than 35%) (Whanger 1998).
Disease Prevention And Treatment by Life Extension Foundation, page 242

Selenium has been used in combination with vitamin A and vitamin E to reduce the toxicity of chemotherapy drugs, particularly Adriamycin (Faure et al. 1996; Vanella et al. 1997). The synergistic effect of vitamin E and selenium together to enhance the immune system is greater than either alone. A new form of selenium is Se-methylselenocysteine (SeMC), a naturally occurring selenium compound found to be an effective chemopreventive agent. SeMC is a selenoamino acid that is synthesized by plants such as garlic and broccoli. SeMC has been shown to induce apoptosis in certain ovarian cancer cells (Yeo et al. 2002) and to be effective against breast cancer cell growth both in vivo and in vitro (Sinha et al. 1999). SeMC has also demonstrated significant anticarcinogenic activity against mammary tumorigenesis (Sinha et al. 1997). Moreover, a study has demonstrated that SeMC is one of the most effective selenium chemopreventive compounds, inducing apoptosis in leukemia HL-60 cell lines (Jung et al. 2001a). Some of the most impressive data suggest that exposure to SeMC blocks clonal expansion of premalignant lesions at an early stage. This is achieved by simultaneously modulating certain molecular pathways that are responsible for inhibiting cell proliferation and enhancing apoptosis (Ip et al. 2001). Unlike selenomethionine, which is incorporated into protein in place of methionine, SeMC is not incorporated into any protein, thereby offering a completely bioavailable compound for preventing cancer. Therefore, 200—400 mcg of SeMC a day is suggested for cancer patients. Please note that selenium also possesses antioxidant properties, so its use before, during, or immediately after chemotherapy could theoretically inhibit the actions of certain chemotherapy drugs.
Disease Prevention And Treatment by Life Extension Foundation, page 277

Scientists have confirmed that vitamins C and E along with the mineral selenium afford some prostate cancer prevention. This is not surprising to anyone who understands diet, biochemistry, and how antioxidants work. Glutathione peroxidase destroys free radicals and superoxides. Its name means that it destroys peroxides (the potent oxidants that form in tissues) and uses glutathione as a helper. Glutathione requires selenium to function; and wherever selenium is at work, vitamin E can’t be far away because they function together.
20 Natural Ways To Reduce The Risk Of Prostate Cancer By James Scala PHD, page 54

For prostate cancer management, stay on a low fat diet, eat tomato products often, take a multivitamin, vitamins C, E and selenium.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 151

Men with higher intakes of antioxi-dants such as vitamin C, vitamin E, and the trace mineral selenium have lower levels of prostate cancer.
Alternative Cures by Bill Gottlieb, page 519

Selenium Statistics

In a December 1996 article in the Journal of the American Medical Association, Dr. Larry Clark presented evidence that supplemental selenium could reduce cancer death rates by as much as 50%. 1,312 patients were given 200 mcg. of selenium daily. The patients receiving selenium had a rise of 67% in their blood selenium level. 
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 148

The patients receiving selenium had a 67% decrease in cancer of the prostate, a 58 percent decrease in colon or rectal cancer and a 45% decrease in lung cancer. This suggests that possibly up to 100,000 lives a year might be saved in the USA by the simple addition of selenium to the diet.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 149

An article in the Journal of the American Medical Association (JAMA) by Clark et al. (1996) showed that 200 mcg of supplemental selenium a day reduced overall cancer mortality by 50% in humans compared to a placebo group not receiving supplemental selenium. This 9-year study demonstrated that a low-cost mineral supplement could cut the risk of dying from cancer in half in certain individuals.
Disease Prevention And Treatment by Life Extension Foundation, page 1255

In a recent five-year study of nearly 30,000 rural Chinese people, researchers from the NCI found that daily doses of these three nutrients reduced cancer deaths by 13%.
Alternative Medicine by Burton Goldberg, page 590

But what if you already have cancer? Again, the research shows a prolongation of lifespan with proper supplementation. In a study in Cancer Letters (Evangelou et al. 1997), animals with malignant tumors given high doses of vitamins C and E and selenium manifested a significant prolongation of the mean survival time. Complete remission of tumors developed in 16.8% of the animals.
Disease Prevention And Treatment by Life Extension Foundation, page 1256

Dr. Raymond Shamberger was also among the first to discover the link between low selenium content in the soil and increasing numbers of deaths from cancer. In 1976, he pointed out that the cities and states with high selenium content in the soil also had significantly lower rates of cancer, especially of the digestive and urinary systems.
Antioxidants Against Cancer by Ralph Moss PhD, page 77

A Powerful Antioxidant „selenium is a crucial mineral in the battle against prostate cancer,” says Dr. Schachter. In one study of hundreds of men, a daily intake of 200 micrograms of selenium cut the incidence of prostate cancer by 60 percent.
Alternative Cures by Bill Gottlieb, page 518

The statistics for breast cancer are particularly striking. „The higher the selenium, the lower the breast cancer,” said Prof. Ladas. Similar associations have been found with leukemia, as well as cancers of the intestines, rectum, ovary, prostate, lung, pancreas, skin and bladder. In Yugoslavia, scientists studied 33 patients with breast cancer. These women had selenium levels in their bloodstream only half those of healthy volunteers.
Cancer Therapy by Ralph W Moss PhD, page 112

Although the study failed to show the effectiveness of selenium in altering the course of either basal or squamous cell carcinoma, selenium impacted the incidence of other types of malignancies with amazing success (Clark et al. 1996). The overall reduction in cancer incidence was 37% in the selenium-supplemented group; a 50% reduction in cancer mortality was observed over a 10-year period. The following are the site-specific reductions in cancer incidence observed in the study: colon-rectal cancers (58%), lung cancer (46%), and prostate cancer (63%). A selenium deficiency appears to increase the risk of prostate cancer fourfold to fivefold. It was determined that, as the male population ages, selenium levels decrease, paralleling an increase in prostate cancer (Brooks et al. 2001).
Disease Prevention And Treatment by Life Extension Foundation, page 242

In a study published in the journal of the National Cancer Institute, the relationship between serum levels of selenium and the development of upper digestive tract cancer was explored (Mark et al, 2000). The relative risk of esophageal cancer was 0.56 in individuals in the highest quartile of selenium level compared with those in the lowest quartile. The corresponding relative risk of gastric cardia cancer was 0.47. Based on the data, the researchers calculate that 26.4% of esophageal and gastric cardia cancers are attributable to low selenium levels.
Disease Prevention And Treatment by Life Extension Foundation, page 242

Selenium Recommendations

The Recommended Daily Allowance (RDA) is 50 to 100 micrograms (not milligrams) but few people get even that much. Selenium is so important that I believe that practically every adult should take a 200 microgram selenium supplement every day. This is readily available in health food stores at a minimal price. Organic selenium derived from yeast may be better absorbed man the mineral form, sodium selenite. Very high doses of either can be toxic, however, and should only be taken under a doctor’s prescription. To summarize: selenium has a strong ability to prevent cancers, especially of the internal organs. There is no evidence that selenium interferes with chemotherapy, radiation or a combination of both. On the contrary, there is evidence that it decreases the side effects of such treatments 
Antioxidants Against Cancer by Ralph Moss PhD, page 81

The supplements that I’d recommend for cancer prevention are the antioxidants: vitamins C and E, beta-carotene, and the mineral selenium.
Anti-Aging Prescriptions by James Duke PhD, page 90

Moderate doses of zinc, beta-carotene, selenium and vitamin E are safe and inexpensive. I believe these results are valid and are an accurate reflection of what antioxidants can do. The finding that two terrible cancers could be prevented by a few pennies worth of supplements received little attention in the mainstream media.
Antioxidants Against Cancer by Ralph Moss PhD, page 83

The National Academy of Sciences advises that no more than 150 micrograms of selenium be taken orally daily. But Revici’s „bivalent negative selenium”— a combination of the mineral with various organic substances, such as the fatty acids of sesame oil—is said to be so non-toxic that huge amounts, up to one million micrograms, have been injected (in the treatment of drug addiction), apparently without any ill effects. In the treatment of cancer the dosage is generally about 10,000 micrograms, still nearly one hundred times the National Academy of Science’s recommended dose.
Cancer Therapy by Ralph W Moss PhD, page 112

But in the meantime, I will continue to take my 200 micrograms of selenium a day—the same dose used in the study—and I suggest that you do, too. Excess selenium has been associated with toxicity, so don’t go overboard. If you’re not fond of popping pills, you can get 120 micrograms of selenium in just one Brazil nut. Buy the shelled kind—they’re grown in a central region of Brazil where the soil is richest in the mineral. Other good sources are tuna fish, seafood, wheat germ, and bran.
Ask Dr Weil by Andrew Weil MD, page 207

While everyone needs selenium on an everyday basis, there are certain situations in which the human need for selenium may be increased, or in which additional selenium may be helpful in the treatment of a disease. If you are a male, your selenium needs are greater than if you are female. If you suffer from heart disease or muscular disorders, additional selenium may help you. The same can be said if you suffer from cataracts, diabetes, cystic fibrosis, liver necrosis, iron deficiency anemia, joint problems, heavy metal poisoning, or cancer.
Complete Guide Health Nutrition by Gary Null, page 479

Now, Dr. Mark A. Nelson, a professor and researcher at the Arizona Cancer Center, says, „The Nutritional Prevention of Cancer (NPC) Trial tripled the intake and suggests that higher levels of selenium may be necessary for cancer prevention.” Until nutritionists conduct more research, though, no one can recommend the best, safest amount you should get. Experts warn selenium is a toxic mineral, which means too much of it, especially from supplements, is unsafe.
Eat and Heal by the Editors of FC&A Medical Publishing, page 98

Doctors at the Chinese Academy of Medical Sciences concluded that selenium supplements were a safe and effective food supplement for people. There have also been a number of reports of selenium’s toxicity or even its alleged ability to cause cancer. There is no question that excess selenium in the soil (in the form of its compounds, selenite or selenate) can kill grazing animals and could probably in sufficiently large doses kill humans as well. The symptoms of selenium poisoning are readily apparent without a doctor’s assistance, according to Dr. Gerhard Schrauzer, a world expert on the topic. These symptoms include a heavy garlic odor, pallor, nervousness, depression, a metallic taste, skin eruptions, irritability, discolored teeth and hair loss. There is some doubt about the carcinogenicity studies. For instance, one study showed toxic effects for inorganic, but not organic, forms of the mineral.
Cancer Therapy by Ralph W Moss PhD, page 112

General / History of Selenium

Selenium (Se) is a metal that is chemically similar to sulfur. It was first discovered in 1817 and because of its silvery color was named for Selene, the ancient goddess of the moon. Selenium is an essential component of two important antioxidant enzymes and is also the helpmate of vitamin E. 
Antioxidants Against Cancer by Ralph Moss PhD, page 76

Initially, selenium’s importance in human health was underrated. In fact, its main use in conventional medicine was as a treatment for dandruff!
Antioxidants Against Cancer by Ralph Moss PhD, page 76

Strange as it may seem, toenail levels of selenium are considered a good indicator of long-term selenium intake. They found that the people whose toenails had the highest levels of selenium had half of the rate of lung cancer compared with those whose toe-nails were low in selenium.
Healing With Vitamins by Alice Feinstein, page 143

Emmanuel Revici, MD based his treatment on correcting an imbalance between fatty acids and sterols in the cancer patient; called „biological dualism”. Revici was considered a very dedicated physician and developer of selenium as an anti-cancer agent. -Ewan Cameron, MD, a Scottish surgeon first popularized the use of high dose vitamin C in terminal cancer patients.
Beating Cancer With Nutrition by Patrick Quillin, page 45

Some scientists still do not accept the need for selenium supplements and argue against its protective effect against cancer and other diseases. Others endorse the value of moderate amounts of selenium added to the diet. In the laboratory, selenium has shown a wide range of anticancer effects.
Cancer Therapy by Ralph W Moss PhD, page 109

Aside from Revici’s work, little has been done to investigate the use of this mineral as a cancer treatment. In 1911, Prof. August von Wasserrman achieved growth inhibition, shrinkage and eventually the disappearance of tumors by injecting selenium directly into mouse tumors. Four years later, two doctors caused the shrinkage and the eventual disappearance of small tumors in cancer patients, although larger tumors failed to respond.
Cancer Therapy by Ralph W Moss PhD, page 112

After critically examining this book, I came to the conclusion that Dr. Revici is an innovative medical genius, outstanding chemist and a highly creative thinker [emphasis added]. I also realized that few of his medical colleagues would be able to follow his train of thought and thus would be all too willing to dismiss his work. Because of my own professional interest in selenium, let me merely focus on this aspect of his work. Selenium containing medications were introduced into cancer therapy as early as 1911 by none less than the great physician August von Wasserman. Working with experimental animals, von Wasserman was able to show his selenium compounds produced liquefactive necrosis of solid tumors, an unheard of event at the time, hailed as a major success. However, von Wasserman’s compounds were too toxic and thus could not be employed in the treatment of human cancer. Dr. Revici deserves credit for having discovered pharmacologically active selenium compounds of very low toxicity. The same was achieved years later by one other great physician, Dr. Klaus Schwarz, in collaboration with a leading organic chemist, Dr. Arne Fredga, of Uppsala University. The National Cancer Institute has recognized the importance of selenium only within the past few years. Would one thus not have to conclude that Dr. Revici, in this one instance, was 40 years ahead of his time? The same could be said for many of his other researches which form the basis of his therapy.
Choices In Healing by Michael Lerner, page 614

Dr. Gerbhard Schauzer, a biochemist at the University of California in San Diego, … believes that if every woman in America began taking selenium supplements today or followed a diet high in selenium, the breast cancer rate in this country would decline drastically in a few years.
Miracle Medicine Herbs by Richard M Lucas, page 16

Asia has considerable quantities of selenium in its soil, making the Asian diet rich in the mineral; not surprisingly, cancer and heart disease occur considerably less often in Asian cultures than in the West.
Optimum Health by Stephen T Sinatra MD, page 123

Additional Benefits of Selenium

Antioxidants, like beta carotene, vitamin C, vitamin E, and selenium appear to enhance the effectiveness of chemo, radiation, and hyperthermia while minimizing damage to the patient’s normal cells; thus making therapy more of a „selective toxin.” An optimally nourished cancer patient can better tolerate the rigors of cytotoxic therapy. 
Beating Cancer With Nutrition by Patrick Quillin, page 18

Patients with advanced rectal cancer were treated with a combination of selenium, the drug 5-FU, and radiation. Scientists reported a protective effect of selenium on quality of life.
Antioxidants Against Cancer by Ralph Moss PhD, page 80

Selenium-deficient animals have more heart damage from the chemo drug, adriamycin.43 Supplements of selenium and vitamin E in humans did not reduce the efficacy of the chemo drugs against ovarian and cervical cancer. Animals with implanted tumors who were then treated with selenium and cisplatin (chemo drug) had reduced toxicity to the drug with no change in anti-cancer activity. Selenium supplements helped repair DNA damage from a carcinogen in animals. Selenium was selectively toxic to human leukemia cells in culture.
Beating Cancer With Nutrition by Patrick Quillin, page 56

While most nutritionists agree on the importance of growth (proliferative) nutrients, few nutritionists respect the importance for anti-proliferative nutrients. For every force in the body, there must be an opposing force to regulate that mechanism. There are agents that cause fluid loss from the kidneys (diuresis) and other agents that stem this fluid loss when it is excessive (anti-diuretic hormone). Just as there is a need for nutrients to augment growth, there is a need for nutrients to control excessive growth and shut down the process. Selenium, fish oil, garlic, Cat’s claw, Maitake D-fraction, vitamin E succinate, vitamin K, quercetin, genistein, and bovine cartilage all may assist the cancer patient in this manner.
Beating Cancer With Nutrition by Patrick Quillin, page 80

Vitamin E and selenium supplements in animals helped to reduce the heart toxicity from adriamycin. Selenium and vitamin E supplements were given to 41 women undergoing cytotoxic therapy for ovarian and cervical cancers, with a resulting drop in the toxicity-related rise in creatine kinase.
Beating Cancer With Nutrition by Patrick Quillin, page 107

One of the foremost selenium investigators, Gerhard Schrauzer of the University of California at San Diego, says: Apart from its functions as an essential micronutrient, selenium also appears to have other physiological functions in which it acts as a physiological resistance factor [emphasis added]. Its cancer protecting effects fall into this category. In addition, selenium protects against free radicals, mutagens, toxic heavy metals and certain bacterial, fungal and viral pathogens. The selenium requirement increases under stress, just as the requirement for certain vitamins increases during infections. Selenium, according to Schrauzer, is most effective as a form of nutritional cancer prophylaxis. In animal research, its protective effect is greater the earlier in life it is given, and its shielding effect against virally induced cancer disappears if the nutrient is no longer fed to the animal. Nevertheless, selenium does have an effect on slowing the rate of growth of established spontaneous or transplanted breast tumors in animals, and in reversing the development of some malignant cell lines when used at pharmacological levels. Further, selenium has shown a general capacity to stimulate the immune system in several animal models, which may add to its anticancer effects. It is of special relevance to cancer patients undergoing chemotherapy that selenium „has by now been shown to prevent or retard tumorigenesis induced by virtually all the major known carcinogens,” probably, Schrauzer believes, „by modulating the rate of cell division.”
Choices In Healing by Michael Lerner, page 612

Just as selenium protects you against toxic metal poisoning, it can also protect you against radiation, whether you are exposed to it through the environment or more directly through medical treatments. A particularly effective form of selenium for this purpose is selenoaminoacid compounds (selenium plus amino acids). Selenium also protects you against compounds called epoxides, as it breaks them down. What are epoxides? Formed when an enzyme named aryl hydrocarbon hydroxylase binds with a carcinogenic substance, epoxides could be called the immediate cause of cancer. The carcinogens cause your body to produce them, and then cancer may ensue.
Complete Guide Health Nutrition by Gary Null, page 483

Reports from Germany indicate that selenium supplementation in patients undergoing radiation therapy for rectal cancer improved quality of life and reduced the appearance of secondary cancers (Hehr et al. 1997) It appears that selenium acts as an immunologic response modifier, normalizing every component of the immune system (Life Extension Report 1995).
Disease Prevention And Treatment by Life Extension Foundation, page 243

Macrophages—those garbagemen of the bloodstream—are capable of keeping your body clear of tumor cells. Also, since they produce interferon, they can help eliminate the viruses that cause some forms of cancer. But to do their job properly, they need adequate selenium.
Complete Guide Health Nutrition by Gary Null, page 483

Some of the known natural compounds that can reduce insulin resistance include omega-3 fatty acids, curcumin, flavonoids, selenium, and vitamin E. Dietary risk factors must be managed. Therefore, besides restricting dietary sugars, individuals should eat an adequate amount of fruits and vegetables because phytochemicals in fruits and vegetables act as potent anticancer agents.
Disease Prevention And Treatment by Life Extension Foundation, page 598

Selenium can prevent solar damage, pigmentation and dark spots, but because the selenium content of soil varies across the country, not everyone is getting enough to be beneficial,” says Dr. Burke, citing the Southeast in particular as an area deficient in selenium. To quench the free radicals caused by sun exposure and to prevent skin damage, Dr. Burke recommends daily supplements of 50 to 200 micrograms of selenium in the form of 1-selenomethionine, depending on where you live and your family history of cancer. Selenium can be toxic in doses exceeding 100 micrograms, so if you’d like to try this therapy to protect your skin, you should discuss it with your doctor.
Healing With Vitamins by Alice Feinstein, page 64

The importance of selenium to cardiovascular health was demonstrated in the provinces of China where the mineral was deficient. This correlation can be seen throughout the world. Ray Shamberger, M.D., and Charles Willis, M.D., of the Cleveland Clinic in Ohio, reported in 1976 that people who live in low-selenium areas have three times more heart disease than those living in areas where the soil and water are rich in the mineral.
Saturated Fat May Save Your Life by Bruce Fife ND, page 142

Selenium also appears to help stimulate antibody formation in response to vaccines. This immunostimulating effect is also enhanced by vitamin E; the presence of these two nutrients can increase antibody formation by 20-30 times, as shown by research.
Staying Healthy With Nutrition by Elson M Haas MD, page 213

Selenium may also aid in protein synthesis, growth and development, and fertility, especially in the male. It has been shown to improve sperm production and motility. Thus, selenium may prevent male infertility; however, we do not know whether selenium deficiency will actually cause male infertility. These are only some of the conjectures about other selenium functions.
Staying Healthy With Nutrition by Elson M Haas MD, page 213

Selenium Interactions

Certain metals such as lead, cadmium, arsenic, mercury and silver block the action of selenium. . . . Recent laboratory experiments have shown that high doses of zinc block the action of selenium. Therefore, one has to be careful about taking excessive amounts of zinc (over 20 milligrams per day from diet and supplements) while taking selenium [emphasis added]. 
Choices In Healing by Michael Lerner, page 619

I think the selenium and saffron complement one another. Selensaff, a product made by Scientific Botanicals (see Resources), is used in cancer therapy to create a redox effect—a process of improving cell function by enhancing both oxygen uptake and the excretion of oxygen waste.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 148 Zinc is important because it is an antagonist to selenium and may in itself enhance or inhibit different tumors. Selenium in minute quantities is essential to human health. According to Prasad, among the minerals, „only selenium has been shown to have a role in cancer prevention”:
Choices In Healing by Michael Lerner, page 619

Vitamin E and selenium protected animals against the potent carcinogenic effects of DMBA from tobacco.
Beating Cancer With Nutrition by Patrick Quillin, page 164

Selenium acts as an antioxidant and strengthens the body’s immune defense system. Thus, many of the effects which are produced by vitamin E deficiency can be reversed or prevented by selenium. Some laboratory experiments have suggested that the combination of vitamin E and selenium is more effective in preventing cancer than either of them alone.
Choices In Healing by Michael Lerner, page 619

However, one experiment has demonstrated increased susceptibility to DMBA-induced tumors when selenium deficiency was aggravated by high dietary levels of polyunsatu-rated fatty acids, and protection by a physiological supplement of selenium (0.1 pg/g) to the diet (Ip and Sinha, 1981). The interpretation of these results is further complicated because of the varied protocols used in these experiments and the knowledge that selenium interacts with many other nutrients, such as heavy metals in the diet.
Diet Nutrition Cancer by National Research Council, page 169

In some experiments, dietary zinc exceeding nutritional requirements has been shown to suppress chemically induced tumors in rats and hamsters, but when given in drinking water it counteracts the protective effect of selenium in mice…While the evidence on the effect of zinc on tumor development is complex, it strongly suggests that, in general, one should be cautious about taking zinc supplements if one has cancer. And since selenium has a wide spectrum of demonstrable anticancer effects, cancer patients should be particularly cautious with zinc, since it is a selenium antagonist. I have seen many cancer patients taking moderately large amounts of zinc as part of a comprehensive megavitamin nutritional supplement program. In view of the available scientific evidence, this is another critical example of an area where uninformed nutritional supplementation may do harm.
Choices In Healing by Michael Lerner, page 612

In addition, statistically significant protection from high levels of selenium and alpha-tocopherol occurred only when gamma- tocopherol concentrations were also high (Helzl-sourer et al. 2000).
Disease Prevention And Treatment by Life Extension Foundation, page 258

Selenium and co-enzyme Q-10. Exhibits anticancer activity especially in blocking development of colon cancer and spread of breast cancer.
Food Your Miracle Medicine by Jean Carper, page 481


Studies on Selenium and Cancer :

Studies on Selenium and prostate cancer

Studies on Selenium and Anti-Tumor

Studies on Selenium and Anti-Angiogenic

Studies on Selenium and Apoptotic

Studies on Selenium and Chemotherapeutic

There is also an extensive bibliography on Selenium (see last page of DATABASE) :



Zinc acts as a membrane stabiliser, and also as a thymic factor (581).

It is therefore important for the production of T lymphocytes.

With low Zinc content, the working of the fagocytes, cell immunity, antibody immunity and the whole Immune Cascade is reduced (582).

Working together with vitamin E, it inhibits the production of inflammatory prostoglandins and leucotriens.

It is also a component of Superoxide Dismutasis (SOD) and takes part in over 200 known enzymatic reactions, of which many are anti-oxidative and repair DNA.

Organic Zinc is necessary for Laetrile therapy (vitamin B17).


Zinc is found in Aloe Arborescens(see my book), in oysters, herrings, the seeds of Cucurbita maxima or moscata (pumpkin), or in Cucurbita pepo (courgettes), in wholewheat cereals.

It counteracts Copper (which is often toxic for the organism, and found in dried fruit), Zinc reduces its absorption.

Zinc is found in Spices [Anethum graveolens (dill), Pimpinella anisum (anise), Ocimum sanctum or tenuiflorum (basil), Cinnamomum zeylanicum (cinnamon), Elettaria cardamomum (cardamom), Eugenia caryophyllata or Caryophyllus aromaticus (cloves), Coriandrum sativum (coriander), Carum carvi (cumin), Carum nigrum or Nigella sativa (black cumin), Curcuma longa (turmeric), Artemisia dracunculus (tarragon), Melissa officinalis (balm-mint), Mentha species (mint), Myristica

fragrans (nutmeg), Origanum vulgare (oregano), Majorana hortensis (marjoram), Capsicum frutescens, fasciculatum aut annum (cayenne pepper, paprika), Cochlearia armoracia (radish), Rosmarinus officinalis (rosemary), Salvia officinalis (sage), Schinus molle (Brazilian peppertree), Sinapsis arvensis or alba (mustard), Thymus vulgaris (time), Crocus sativus (saffron), Piper nigrum (black pepper), and Zingiber officinalis (ginger)].

An adult should take about 20 milligrams of organic Zinc a day, much more in the case of cancer patients for Laetrile and/or B 17 therapy.


allyl Sulfur (an organo-Sulfur compound) (*)

Diallyl sulfide [DAS], (an organo-Sulfur compound) (*)

Diallyl disulfide [DADS], (an organo-Sulfur compound) (*)

Diallyl trisulfide [DATS], (an organo-Sulfur compound) (*)

(*) which are decomposition products of Allicin Germanium sesquioxide Manganese

Superoxide Dismutasis (SOD),  Selenium derivatives (sodium Selenite, Seleno-DL-Methionine, Se-methyl-selenocysteine)

for studies cited above see last page of database.

Studies on Zinc and cancer

Studies on Zinc and Anti-Tumor

Studies on Zinc and Radioprotective

Studies on Zinc and Antineoplastic

Studies on Zinc and Antiproliferative

Studies on Zinc and Anti-Angiogenic

Studies on Zinc and Apoptotic



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