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Organic and inorganic forms of Germanium
For any therapy, only very pure organic Germanium should be used. The heavy metals (Pb, As, Hg, Cd) should be almost absent, and if they are present should only be in well defined and negligible quantities (<0,1ppm); moreover there must be no traces of Germanium oxide (GeO2).
Inorganic Germanium is toxic for the kidney cells.In its inorganic from Germanium is present in the soil, rocks and coal, together with other minerals from which it can be extracted and transformed industrially into organic Germanium.
Natural organic Germanium
Organic Germanium is found naturally in Allium sativum, Allium cepa, Panax ginseng, Pfaffia paniculataOrganic Germanium is found naturally in some oriental mushrooms: Ganoderma lucidum, Grifola frondosa but this are dangerous
The immune stimulating properties of organic Germanium
The most important property manifests itself in the stimulation of the immune system.
Especially with regard to the Natural killers, the increase in cytolytic ability already begins from the second day, reaching its peak on the fourth day, finally exhausting itself a week from the last administration; an increase of 30% can be seen in the cytolysis, compared to control groups treated with a placebo.
Studies on the anti-cancer effect of Germanium have also shown the role it plays in activating the T lymphocytes, the macrophages, the lymphokines and Gamma interferon: Germanium stimulates the T lymphocytes to produce lymphokine, MIF (Migration Inhibition Factor), MAF (Macrophage Activation Factor), chemotactic factors, CSF (Colony Stimulating
Factors) and lymphotoxins.
The subsequent Immune Cascade also establishes an activation of the macrophages which take part in the lysis of the cancer cells in an effective ratio of 1:1, like cytotoxic T lymphocytes, Natural killers and Killers. On the other hand,NO activation of the
granulocytes has been shown, but the more difficult capacity for anti-cancer activation is known, which requires a strength ratio of 40:1 between the granulocytes and the cancer cells.
Anti-oxidant property of organic Germanium
The specific action of Germanium 132 is on a biochemical level, since it renders oxygen available for the cells, with the important implications therefore for cancer. Among these are a large number of degenerative pathologies, pathologies of the metabolism or caused by some deficiency. In particular, its biochemical characteristic is that it acts as a semiconductor in the transport processes of the electrons inside the cells, thus allowing the formation of ATP with the final production of non toxic molecular substances (water). Its anti-oxidant actionagainst cysteine is also important.
Cell respiration refers to the catabolic processes by means of which the nutritive substances, glucose for example, are broken up inside the cells, releasing energy which is then used to form Adenosine-Tri-Phosphate (ATP, cell energy).
With organic Germanium an exothermic reaction takes place, which supplies oxygen and hydrogen to the individual cells of the organism. The stable and continuous flow of oxygen and hydrogen to all parts of the organism facilitates and strengthens oxidation and reduction inside the cells: oxidation takes place either with the acquisition of oxygen or with the loss of hydrogen.
Any reaction which creates energy inside a cell is an oxidant reaction.
Oxidation can happen in two ways:
1) the combination of oxygen with other elements
2) the removal of hydrogen atoms from the compounds.
Basically, oxidation of nutritive substances is the gradual removal of pairs of hydrogen atoms from the support molecules, because when the pairs of hydrogen atoms are removed, they take with them their electron pairs. In this way oxidation of glucose in Krebs’ cycle occurs with the gradual removal of hydrogen atoms.
Where a substance loses electrons, becoming oxidated and losing energy, there is another substance which acquires them, thus becoming reduced, that is to say, acquiring energy.
The hydrogen atoms which are removed are sent to the electron transport chain, which converts the energy taken from the oxygen, to transport the electrons along the whole length of the chain.
In the end the hydrogen atoms which are removed combine with the molecular oxygen (creating water), and the resulting energy is freed as ATP, and thus available for the cells.
The immune cells, such as the very delicate lymphocytes, thus acquire an energy capacity which enables them to do their work even in a hypoxic environment such as cancer tissue, famously characterized by High Interstitial Fluid Pressure (H.-I.F.P. see: see: Jain R.K.: Barrier to Drug Deliver y in Solid Tumors, Scientific American, Science, July,1994). Vice versa the cancer cells, which have become oxidated both because of the removal of hydrogen and also by the endocell molecular reaction with oxygen, both induced by the presence of organic Germanium, as a result are more exposed to the phenomena of apoptosis and pseudo-apoptosis, being poor in enzymatic complexes which would perform an endo-nuclear repair of their own DNA, which on the contrary are characteristic of normal cells which have not been degenerated by cancer.
Anti-ischemic properties of organic Germanium
It acts as an electro-nutrient in hypoxic states, which are frequent in chronic degenerative pathologies, such as cardio-vascular or neuro-vascular pathologies or those of the metabolism in general.
Organic Germanium stimulates the ability to increase the availability of oxygen for the cells and helps eliminate unpaired electrons. This makes it particularly invaluable in cases of acute ischemia (miocardic infarct, strokes and asphyxiation by carbon monoxide).
Modifications of the biochemical and functional parameters of the organism induced by organic Germanium
The catalytic effects on the use of oxygen are seen in the renormalization of the biochemical and functional parameters of the organism in a time-frame of between 4 to 6 weeks:
1) Regularization of the partial pressure of carbon dioxide in the blood.
2) Regularization of the values of hematic glucose, above all in diabetic patients.
3) Reduction of the triglycerides.
4) Regularization of total cholesterol with an increase in the ratio of HDL/LDL.
5) Normalization of bilirubin.
6) Normalization of uric acid.
7) Regularization Na / K, Ca / Mg.
8) Increase in haemoglobin.
9) Lymphocite rebalance in chronic infectious diseases. (HIV/AIDS).
10) Protection from oxidative damage induced on the DNA by ionizing radiation.
Anti-amyloidosis property of organic Germanium
Amyloidosis is often induced by Chemo-Therapy or radio-therapy.
Germanium protects against the accumulation of amyloid substances, a process which is generated by a protein imbalance in the catabolism and often associated with chronic inflammatory conditions.
Analgesic property of organic Germanium
Organic Germanium has analgesic effects, acting as a neuro-modulator. This happens through the inhibition of enzymes (peptidase such as Aminopeptidase, Carboxypeptidase, dipeptidil- Aminopeptidase and dipeptidil-Carboxypeptidase [also known as Enkefalinase B and D]) which downgrade the endorphins.
Since it is difficult to find natural organic Germanium, and it is very expensive, the following proposal could be useful: to use inorganic Germanium (which is much less expensive than organic Germanium) in the cultivation of plants with a great capacity for trace-mineral uptake. The cultivation of Equisetum arvense, Medicago sativa, Rosmarinus officinalis and Aloe Arborescens could useful. Besides being high in Germanium , Aloe Arborescens is a powerful cancer treatment by its own and you will find more details in my book, including how to make it at home.
There is an ample bibliography about organic Germanium: 107, 110, 119, 139, 174, 193, 237, 249, 269, 336, 357, 386, 399, 440, 441, 460, 476).
for studies cited above see last page of scientific studies database click here.
SEE also: Mainwaring MG: Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide, Chest, 117, pp. 591-593, 2000; Chest, 117, pp. 307-308, 2000
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